Results 81 to 90 of about 61,913 (296)

Towards a framework for evaluating potential sites for transit supportive development in South East Queensland

open access: yes, 2005
The regional plan for South-east Queensland has adopted the concept of transit oriented development (TOD) to manage the rapid growth in the region. This suggests a political commitment to a form of development that is supportive of mass transit and ...
Bajracharya, Bhishna, Khan, Shahed
core  

Flexing service schedules: Assessing the potential for demand-adaptive hybrid transit via a stated preference approach

open access: yes, 2017
This paper assesses the demand for a flexible, demand-adaptive transit service, using the Chicago region as an example. We designed and implemented a stated-preference survey in order to (1) identify potential users of flexible transit, and (2) inform ...
Frei, Charlotte   +2 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Central Asian transport corridors issue in the scientific literature

open access: yesHalyk̦aralyk̦ k̦atynastar ža̋ne halyk̦aralyk̦ k̦u̇k̦yk̦ seriâsì, 2019
The article describes the main views of domestic and foreign experts on the development of transport corridors in Central Asia. The relevance of the problem is explained by the expansion of transport infrastructure in the Central Asian region within the
F. Kukeyeva   +3 more
doaj  

Transit in Regional Economic Development: The Case of the Kaliningrad Exclave

open access: yesEuropean Spatial Research and Policy, 2020
The study analyses the role of the transit function in the development of a regional transport system drawing on the example of the Kaliningrad exclave region (Russia).
Ksenia Yu. Voloshenko   +2 more
doaj   +1 more source

Active Transportation by Transit-Dependent and Choice Riders and Potential Displacement of Leisure Physical Activity

open access: yesJournal of Planning Education and Research, 2015
Public transit users are expected to have higher levels of active transportation (AT, walking and bicycling) because they often need to walk to and from transit. Surveys in Baltimore and Seattle ( n = 1,622) revealed that transit users performed more AT than nonusers, especially when dependent on transit.
Lachapelle, Ugo   +4 more
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

KAZAKHSTAN ECONOMIC SAFETY RISE

open access: yesМодернизация, инновация, развитие, 2016
Economic safety of the Republic of Kazakhstan essentially depends on how the Republic’s transit potential is used and how internal demands in energy resources are met.
G. G. Rakhmatulina
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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