Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Transit potential of Kazakhstan in the Silk Road Economic Belt
This article is devoted to the analysis of Kazakhstan’s transit potential in the Silk Road Economic Belt. The transit potential of the country is part of the market infrastructure that must be developed for the successful functioning of the entire ...
A. Myrzahmetova, Syan Gi ᅠ
doaj
Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport [PDF]
AbstractBcl-2 family proteins are key regulators for cellular homeostasis in response to apoptotic stimuli. Bcl-xL, an antiapoptotic Bcl-2 family member, undergoes conformational transitions, which leads to two conformational states: the cytoplasmic and membrane-bound.
Rajan, Sreekanth +13 more
openaire +4 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Two-dimensional metal-insulator transition as a potential fluctuation driven semiclassical transport phenomenon [PDF]
We theoretically consider the carrier density tuned (apparent) two-dimensional (2D) metal-insulator-transition (MIT) in semiconductor heterostructure-based 2D carrier systems as arising from a classical percolation phenomenon in the inhomogeneous density landscape created by the long-range potential fluctuations induced by random quenched charged ...
Sarma, S. Das, Hwang, E. H., Li, Qiuzi
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Analysis of Kazakhstan’s transport industry in modern conditions
In the circumstances of the modern world countries that are located far from the main world mar- kets and don’t have access to the sea, as well as countries that are not open for cooperation in the field of world transport relations, are destined to ...
А. Мырзахметова
doaj
The aim of transit-oriented development (TOD) is to create a livable urban environment by improving the integration between land-use and transportation systems.
Eden Atsbeha Teklemariam, Zhongwei Shen
doaj +1 more source
Strategic Planning for Port Development: Improvement of Container Transit from the Iranian Southern Ports Terminals [PDF]
The author attempts to highlight the significance of the Iranian southern ports development strategy planning which allows for the maximum container transit with minimum resources such as service capacities, human resources, and financial potential in ...
Homayoun Yousefi
doaj +1 more source
An overview of Mexico's energy transition potential for the transportation sector (2050)
Presentation describing methods, and findings from OSeMOSYS (Open Source Energy Modeling System) runs for Mexico in completion of the 2022 Energy Modelling Platform for Latin America and the Caribbean training.
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