Results 61 to 70 of about 61,913 (296)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Frontiers of Architectural Research, 2020 The aim of transit-oriented development (TOD) is to create a livable urban environment by improving the integration between land-use and transportation systems.
Eden Atsbeha Teklemariam, Zhongwei Shen
doaj +1 more source
Strategic Planning for Port Development: Improvement of Container Transit from the Iranian Southern Ports Terminals [PDF]
TransNav, 2013 The author attempts to highlight the significance of the Iranian southern ports development strategy planning which allows for the maximum container transit with minimum resources such as service capacities, human resources, and financial potential in ...
Homayoun Yousefi
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An overview of Mexico's energy transition potential for the transportation sector (2050)-Poster
, 2022 Poster describing methods, and findings from OSeMOSYS (Open Source Energy Modeling System) runs for Mexico in completion of the 2022 Energy Modelling Platform for Latin America and the Caribbean training.
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Institutional and Organizational Features of the Cross-Border Freight Traffic in the Conditions of Integration among Former Soviet States. Part 2 [PDF]
Экономика региона, 2015 The article considers the technical, technological, institutional and organizational barriers of cross-border transportation of goods. The study uses an institutional approach as a methodological alternative to other approaches.
Valery Anatolevich Tsvetkov +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Multimodal TransportationHuman mobility is mostly dominated by the use of private cars, leading to disproportionate carbon emissions, resource consumption, traffic jams, and pollution.
Puneet Sharma +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Transport corridors of the Republic of Kazakhstan and prospects of their development.
Хабаршысы. Экономика сериясы, 2016 Kazakhstan is located in the center of Eurasia, in the midst of communication flow between Europe and Asia. The country has a huge transit potential. Further development of the country’s transit potential in the field of international transport, which ...
K. E. M. S. S. S. Мukhtarova Мukhtar Мadenova
doaj