Results 121 to 130 of about 795,414 (305)
Sustainable mobility at the EU level - and the new transport White Paper [PDF]
, 2011 The main messages of the paper in four points are the following: (1) The environmental target for 2050 (sixty percent emission decrease, oil dependence decrease) is a very progressive vision, clear target.
Fleischer, Tamás
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
THE NEW CONCEPT OF DYNAMIC TRANSPORT PLANS
Perner’s Contacts, 2014 The paper deals with a new concept of dynamic transport plan. As we know in the current status not all cities have a key strategic documents for the development of transport. The concept of dynamic plan for responding to any changes in the area, traffic
Marián Gogola
doaj
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
High-speed railway connections – the next Slovene centennial infrastructure project? [PDF]
Urbani Izziv, 2005 The debate about building a network of high speed railway connections on Slovene territory after full membership in the EU is becoming ever more pending.
Aljaž Plevnik
doaj
The Green Investment Report: The Ways and Means to Unlock Private Finance for Green Growth [PDF]
, 2013 This report is a first step by the Green Growth Action Alliance to deliver on the G20 Leaders' request. It aims to provide a common point of reference to guide policy-makers, financial institutions and investors as they seek to better understand, and ...
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Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
NUMBERS OF ROAD FREIGHT TRANSPORT IN KEMEROVO REGION IN 1945 –1965
Вестник Кемеровского государственного университета, 2014 The paper aims at analyzing the growing dynamics of road freight transport and motor transport companies in Kemerovo region in 1945-1965. The author analyzes achieve documents, statistical books, papers and some Internet sources addressing this topic ...
A. S. Baturin
doaj
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source