Results 101 to 110 of about 5,287,692 (251)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Social exclusion and transport policy [PDF]

open access: yes, 2004
This paper is a review of social inclusion in the specification by central government of policy instruments for local government. It forms part of the scooping study on Accessibility and User Needs in Transport (AUNT) funded by the EPSRC Sustainable ...
Titheridge, H.
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Possibilities for Using NoSQL Databases in Information Systems in Transport [PDF]

open access: yes, 2016
The article presents directions for development of end-user-oriented information systems in transport. Characteristics of databases belonging to the trend of NoSQL have been enumerated as well as the represented data models.The example of a relational ...
Czerepicki, Andrzej; Warsaw University of Technology, Faculty of Transport
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Point to point transport

open access: yes, 2016
The Point to Point Transport (Taxis and Hire Vehicles) Bill 2016, passed by the NSW Parliament on 22 June 2016, covers flexible transport services that can take customers on the route they choose, at the time that suits them.
Transport for NSW
core  

Cycling on the Verge? Exploring the Place of Utility Cycling in Contemporary New Zealand Transport Policy [PDF]

open access: yes, 2014
Efforts to increase cycling as a mode of transport (utility cycling) occur at central, regional and local levels of government through a range of supportive strategies, research, and guidelines.
Smith, Megan
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

THE NEW CONCEPT OF DYNAMIC TRANSPORT PLANS

open access: yesPerner’s Contacts, 2014
The paper deals with a new concept of dynamic transport plan. As we know in the current status not all cities have a key strategic documents for the development of transport. The concept of dynamic plan for responding to any changes in the area, traffic
Marián Gogola
doaj  

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