Results 91 to 100 of about 800,407 (302)

Example of rational modal split in the transport network technical and economic issues

Forum Scientiae Oeconomia, 2014
In recent decades, almost all over the world, the issue of sustainable de- velopment has been strongly promoted in the transport policy. Initially, it applied chiefly to creating specific documents defining basic terms, for in- stance Brundtland Report (
Ireneusz Celiński, Grzegorz Sierpiński   +1 more
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Sustainable mobility at the EU level - and the new transport White Paper [PDF]

, 2011
The main messages of the paper in four points are the following: (1) The environmental target for 2050 (sixty percent emission decrease, oil dependence decrease) is a very progressive vision, clear target.
Fleischer, Tamás
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

CONCERNING THE PROBLEM OF SEMANTIC CONTRADICTIONS ARISING WHEN USING THE TERMS “INTERMODAL” AND “MULTIMODAL” PASSENGER CARRIAGES

International Journal of Advanced Studies, 2017
This article examines Russian and foreign regulatory documents, concerning the issues of intermodal/multimodal passenger carriages, shows the essence of intermodal transportation in passenger transport, includes the analysis of various approaches to the ...
Norayr Oganesovich Bludyan, Liudmila Andreevna Paramonova   +1 more
doaj   +1 more source

Transportation Business Plan: strategy options document [PDF]

, 1984
This document provides the framework for development of a business plan for establishing and operating the transportation system necessary to support a repository. Section I contains introductory material and defines the plan in terms of policy basis, purpose, and scope of business activities. Section II discusses the evolving strategy that will direct
openaire   +2 more sources

Requirements analysis of the VoD application using the tools in TRADE [PDF]

, 1996
This report contains a specification of requirements for a video-on-demand (VoD) application developed at Belgacom, used as a trial application in the 2RARE project. The specification contains three parts: an informal specification in natural language; a
Huyts, Sander, Wieringa, R.J.
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

E-Commerce in Ports

Promet (Zagreb), 2002
EDI (Electronic Data Interchange) and electronic businessshould be looked upon as a natural evolution in the internationaltrade and transport cycle. One of the principal reasonsfor starting to use EDI are the heaps of documents written,shifted, handled ...
Elen Twrdy, Evelin Vatovec Krmac
doaj   +1 more source