Results 91 to 100 of about 5,287,692 (251)
Changing the climate of public transport : a design research initiative
The Public Transport Design Research Initiative, developed by Monash University’s Faculty of Art & Design and the Institute of Transport Studies in 2005, aims to develop original and innovative design concepts and approaches to address the challenges ...
Coxon, Selby +2 more
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Public transport sector driver behaviour : measuring recklessness using speed and acceleration [PDF]
Conferende theme: Leading transport into the futurePlease cite as follows:Zeeman, A. S. & Booysen, M. J. 2014. Public transport sector driver behaviour: Measuring recklessness using speed and acceleration paper delivered at the 33rd annual Southern ...
Booysen, M.J. +3 more
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Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
DEVELOPING A CYCLING SUBSYSTEM AS PART OF A SUSTAINABLE MOBILITY STRATEGY: THE CASE OF GDANSK [PDF]
Modal share is an important component in developing sustainable transport within a city. In recent years, many cities have set modal share targets for balanced and sustainable transport modes: 30% of public transport and 30% of non-motorized (cycling ...
Romanika OKRASZEWSKA +2 more
doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
STATE REGULATION OF CARGO SECURING FOR ROAD TRANSPORT
This article examines the legal documents governing the securing of cargo in road transport, provides an overview of international experience in the safety of road transport of goods by means of securing.
Nikolay Anatolievich Atrokhov +1 more
doaj
Bridging the divide : design’s role in improving multi-modal transport
For a public transport user to experience an efficient journey, the transport system should demonstrate the network effect (Mees 2000; Nielsen et al. 2005); combining available modes in a network to achieve their best capacity.
Coxon, Selby +2 more
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Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Changes in the interpretation of logistics and transport issues in UE policy
At the beginning of 21st century, UE issued a document in which, in accordance with Lisbon Strategy, basic aspects of UE transport policy were introduced.
Bujak, Andrzej; the International University of Logistics and Transport in Wrocław
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