Results 91 to 100 of about 73,715 (300)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Conventions and Documents in the Road Transport of Goods [PDF]
, 2015 Obavljanje cestovnog prijevoza robe temelji se na licencijama i dozvolama koje je potrebno ishoditi da bi se prijevoz mogao obavljati na legalan način. Za obavljanje javnog cestovnog prijevoza tereta u unutarnjem prijevozu potrebno je ishoditi Licenciju ...
Kušević, Darko
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Driving factors of GHG emissions in EU transport activity [PDF]
, 2017 This research identifies the driving factors of greenhouse gas emissions in transport activity in the EU-28 and the contribution of each of them to its changes during the period 1990-2014. The analysis is based on the STIRPAT model, which is broadened to
Padilla, Emilio +3 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
TRANSPORT DOCUMENTS IN FOREIGN TRADE
, 2021 Vanjska trgovina predstavlja područje internacionalizacije poslovanja. Radi se o segmentu koji podrazumijeva širenje različitih ekonomskih aktivnosti izvan granica koje su usmjerene na domaće tržište. Sve navedeno dovodi do ekstenzivne
Bilandžić, Josip
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
International Journal of Advanced Studies, 2017 This article examines Russian and foreign regulatory documents, concerning the issues of intermodal/multimodal passenger carriages, shows the essence of intermodal transportation in passenger transport, includes the analysis of various approaches to the ...
Norayr Oganesovich Bludyan +1 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Links between production systems and transport : the example of German and French industries [PDF]
Changes in transportation are closely linked to the economic and logistical characteristics of the production system. The aim of this paper is, on the basis of data on the economic context and surveys conducted in France (the 1988 Shipper survey and the ...
Sebastian Schneider +5 more
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