Results 91 to 100 of about 1,627,601 (317)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Intelligent Transport Systems-Technological, Economic, System Performance and Market Views

open access: yesInternational Journal of Technology, 2014
This paper introduces a holistic view to intelligent transport systems (ITS) by providing four different perspectives: the technological, economic, system performance and market views.
Pekka Leviäkangas
doaj   +1 more source

Transport engineering for improving the production and secretion of valuable alkaloids in Escherichia coli. [PDF]

open access: yesMetab Eng Commun, 2021
Yamada Y   +9 more
europepmc   +1 more source

Flow and transport in tissue engineering scaffolds: A network modelling approach [PDF]

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009)   +2 more
core  

Microscopic theory of single-electron tunneling through molecular-assembled metallic nanoparticles

open access: yes, 2003
We present a microscopic theory of single-electron tunneling through metallic nanoparticles connected to the electrodes through molecular bridges. It combines the theory of electron transport through molecular junctions with the description of the ...
A. Nitzan   +25 more
core   +1 more source

DATA MINING APPLICATIONS IN TRANSPORTATION ENGINEERING

open access: yesTRANSPORT, 2003
Data mining is the extraction of implicit, previously unknown and potentially useful information from data. In recent time, data mining studies have been carried out in many engineering disciplines. In this paper the background of data mining and tools is introduced.
openaire   +6 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Design study to simulate the development of a commercial transportation system [PDF]

open access: yes
Seven teams of senior-level Aerospace Engineering undergraduates were given a Request for Proposals (RFP) for a design concept of a remotely piloted vehicle (RPV).

core   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

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