Results 51 to 60 of about 1,760,876 (312)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

About International Conference "Transport Means" [PDF]

open access: yesTransport, 2007
General and statistical information about the 11th International Conference “Transport Means” is presented.
D. Markšaitis
doaj  

Quantum simulation via filtered Hamiltonian engineering: application to perfect quantum transport in spin networks

open access: yes, 2013
We propose a method for Hamiltonian engineering in quantum information processing architectures that requires no local control, but only relies on collective qubit rotations and field gradients. The technique achieves a spatial modulation of the coupling
Ajoy, Ashok, Cappellaro, Paola
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Enhancing thermoelectric figure-of-merit by low-dimensional electrical transport in phonon-glass crystals

open access: yes, 2015
Low-dimensional electronic and glassy phononic transport are two important ingredients of highly-efficient thermoelectric material, from which two branches of the thermoelectric research emerge.
Huang, Xiaoming   +5 more
core   +2 more sources

Fast shuttling of a trapped ion in the presence of noise [PDF]

open access: yes, 2014
We theoretically investigate the motional excitation of a single ion caused by spring-constant and position uctuations of a harmonic trap during trap shuttling processes.
Chen, Xi   +5 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Geotechnical Problems Of The Foundation Of Road Embankments By The Bridge Structures

open access: yesStudia Geotechnica et Mechanica, 2019
This work presents the geotechnical problems occurring in the interaction area between road embankments and the bridge structures in case a subsoil characterised by complex and complicated geological and engineering conditions. These significant problems
Batog Andrzej, Stilger-Szydło Elżbieta
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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