Results 41 to 50 of about 485,603 (310)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Insulated Interlayer for Efficient and Photostable Electron-Transport-Layer-Free Perovskite Solar Cells

open access: yes, 2018
Currently, the most efficient perovskite solar cells (PSCs) mainly use planar and mesoporous titanium dioxide (TiO2) as an electron-transport layer (ETL). However, because of its intrinsic photocatalytic properties, TiO2 can decompose perovskite absorber
Nam Gyu Park (4971223)   +9 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Transport and mixing of chemical air masses in idealized baroclinic life cycles

open access: yes, 2007
The transport, mixing, and three- dimensional evolution of chemically distinct air masses within growing baroclinic waves are studied in idealized, high- resolution, life cycle experiments using suitably initialized passive tracers, contrasting the two ...
Esler, J. G.   +3 more
core   +1 more source

Magnetic topological transistor exploiting layer-selective transport

open access: yesPhysical Review Research, 2023
We propose a magnetic topological transistor based on MnBi_{2}Te_{4}, in which the “on” state (quantized conductance) and the “off” state (zero conductance) can be easily switched by changing the relative direction of two adjacent electric fields ...
Hai-Peng Sun   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Quantifying transport into the lowermost stratosphere using simultaneous in-situ measurements of SF₆ and CO₂

open access: yes, 2008
The seasonality of transport and mixing of air into the lowermost stratosphere (LMS) is studied using distributions of mean age of air and a mass balance approach, based on in-situ observations of SF6 and CO2 during the SPURT (Spurenstofftransport in der
Bönisch, Harald   +4 more
core   +1 more source

Investigating the performance of Tin-based perovskite solar cell with Cadmium Sulphide as etm and graphene as htm using SCAPS-1D

open access: yesФізика і хімія твердого тіла
Solar cells based on lead-free perovskite have demonstrated great potential for renewable energy. The SCAPS-1D simulation software was used in this study to perform device modelling of a lead-free perovskite solar cell of the architecture Glass/FTO/CdS ...
Adeyemi Joshua Owolabi   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Promoting the use of reliable rate based transport protocols: the Chameleon protocol [PDF]

open access: yes, 2010
Rate-based congestion control, such as TFRC, has not been designed to enable reliability. Indeed, the birth of TFRC protocol has resulted from the need for a congestion-controlled transport protocol in order to carry multimedia traffic.
Emmanuel Lochin   +7 more
core   +1 more source

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