Results 91 to 100 of about 38,308 (260)

LIABILITY OF THE TRANSPORTATOR IN THE CASE OF THE RAILWAY TRANSPORT CONTRACT [PDF]

open access: yesChallenges of the Knowledge Society, 2019
When dealing with rail transport, whether we deal with aspects of domestic or international rail transport, the provisions of GO no. 7/2005 for the approval of the Romanian Railways Regulation and the Romanian Rail Transport Regulations for Internal ...
Adriana Elena BELU
doaj  

THE IMPROVEMENT OF HAZARDOUS GOODS TRANSPORTATION TECHNOLOGY

open access: yesTRANSPORT, 2004
This article analyses the conception of the improvement of hazardous goods transportation technology as well as its theoretical principles. Basic organizational aspects of hazardous goods safe transportation are also represented. Effective and safe hazardous goods transportation is possible only using good informational supply.
openaire   +4 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

PROSPECTS OF INTERNATIONAL FREIGHT TRANSPORT IN THE EAST-WEST DIRECTION [PDF]

open access: yesTransport Problems, 2015
The article deals with the assets of building broad-gauge lines in Europe. The delivery time for international transport of goods affects international business in terms of the capital put into goods and subsequently affects its turnover rate.
Paweł DROŹDZIEL   +2 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

CLP Regulation and the transport of dangerous goods.

open access: yesAnnali dell'Istituto superiore di sanita, 2011
Regulations concerning different modes of transport of dangerous goods are well harmonized at global level: they were then looked at as a model for developing Globally Harmonized System of Classification and Labelling of Chemicals (GHS), (on which CLP Regulations is based).
openaire   +3 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Preconditions for Returning Highly-Profitable Shot Lots to Railway Transport

open access: yesВестник Российского экономического университета имени Г. В. Плеханова
The article describes reasons for transition of small shipments from railway transport to automobile one and studies proposals to return highly-profitable shot lots back to the railway transport. Today we can observe a rise in the volume of shot lots and
D. A. Bakunin   +2 more
doaj   +1 more source

CHOOSING A TRANSPORT UNIT FOR THE TRANSPORTATION OF PERISHABLE GOODS

open access: yes, 2023
This thesis discusses the choice and use of a temperature-controlled vehicle for the transportation of perishable goods. It is established that the volume and weight of the transported cargo, the nature of transportation are the main factors when choosing an alternative mode of transport.
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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