Results 111 to 120 of about 38,520 (261)

50-Years Inland Waterway Freight Data in the Rhine-Alpine Corridor. [PDF]

Sci Data
Turpijn B, Baart F, Tavasszy L, van Koningsveld M.   +3 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Research on emergency truck dispatching scheme for the high speed railway freight interruption. [PDF]

PLoS One
Guo S, Hu Z, Zhao S, Feng J.
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Assessing compliance with smoke-free laws in Purbakhola Rural Municipality, Nepal: A cross-sectional observational study. [PDF]

PLOS Glob Public Health
Kc BB, Chand AB, Bam A, Bam TS.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Carbon Footprint of Antibody-Based Drugs and Biologics Using Hybrid Life Cycle Assessment. [PDF]

Clin Pharmacol Ther
Taillemite S, Fenelon M, Scherlinger M, Piffoux M.   +3 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Under-Five Undernutrition Prevalence, Its Inequality, Associated Socio-Economic and Demographic Factors in Uganda: Secondary Analysis of 2019/2020 National Panel Data. [PDF]

Nutr Metab Insights
Orech S, Mine MR, Okello F, Nabachenje P, Nankafu B, Uside KA, Lubaale YM.   +6 more
europepmc   +1 more source

TECHNIQUES OF TRANSPORTATION OF GOODS IN VEHICLES: AN OVERVIEW

The transportation of goods plays a crucial role in the global economy, ensuring the efficient movement of products from manufacturing facilities to distribution centers and ultimately to end consumers. Vehicles serve as the backbone of the transportation industry, offering diverse techniques for moving goods across various distances.
openaire   +2 more sources