Results 161 to 170 of about 66,320 (342)

An Overview On State-of-Art Energy Harvesting Techniques and Choice Criteria: a WSN Node for Goods Transport and Storage Powered by a Smart Solar- Based EH System

, 2017

openalex   +1 more source

Adaptive non-conform behaviour in accident investigations in the road based heavy goods transport sector

, 2021
Christian Henrik Alexander Kuran, Sharon Newnam, Vanessa Beanland   +2 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Scoping Review of the Socioeconomic Value of Working Equids, and the Impact of Educational Interventions Aimed at Improving Their Welfare. [PDF]

Animals (Basel)
Cameron A, Freeman SL, Wild I, Burridge J, Burrell K.   +4 more
europepmc   +1 more source

Transport of Dangerous Goods by Road: Preliminary Data Analysis in March 2020 During COVID-19 Emergency in Italy

, 2020
Fabio Borghetti, Roberto Maja
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

DEPENDENCE OF THE GEOGRAPHICAL STRUCTURE OF INTRACONTINENTAL COUNTRIES’ EXPORTS ON THE TRANSPORTABILITY OF GOODS (A CASE STUDY OF MONGOLIA)

Л. А. Безруков, A. N. Fartyshev   +1 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Enhancing Healthcare Access for Older Adults through Innovative Mobility Solutions Leveraging Public Assets. [PDF]

JMA J
Yokota M, Nakahara S, Nishida M.
europepmc   +1 more source

ROAD TRANSPORT OF GOODS IN INDONESIA: INFRASTRUCTURE, REGULATORY AND BRIBERY COSTS

, 2016
Brasukra G. Sudjana
openalex   +1 more source