Results 191 to 200 of about 38,520 (261)

Drivers of food cost in outer regional, remote, and very remote Australia: a systematic scoping review. [PDF]

BMC Public Health
van Burgel E, Martin C, Dancey J, Cubillo B, Nona F, Miles E, Ferguson M, Day G, Brimblecombe J.   +8 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Challenges in radiopharmaceutical importation across six Southern African Development Community countries: an exploratory study. [PDF]

Front Med (Lausanne)
Mkhombo VG, Mosima L, Summers B.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Hungary's Current Climate Conditions Converge With the North-Mediterranean of the 1980s: A Case Study in Mediterranean Ant Species New to Hungary. [PDF]

Ecol Evol
Csősz S, Laczi M, Herczeg G, Báthori F.   +3 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Research on Axle Type Recognition Technology for Under-Vehicle Panorama Images Based on Enhanced ORB and YOLOv11. [PDF]

Sensors (Basel)
Feng X, Peng L, Tang Y, Liu C, An H.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Sustainable and accessible hemodialysis: life cycle assessment on central acid delivery system. [PDF]

BMC Nephrol
Tsai CL, Fehintola A, Crooijmans G, Vollenbroek J, Duane B, Gerritsen K.   +5 more
europepmc   +1 more source

Tree-based machine learning methods for predicting vehicle insurance claim size. [PDF]

Front Big Data
Terefe EM, Aga MA.
europepmc   +1 more source