Results 191 to 200 of about 38,308 (260)

How to navigate the EU's CBAM trilemma: A review of policy objectives and possible designs. [PDF]

Open Res Eur
Corvino F.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Tree-based machine learning methods for predicting vehicle insurance claim size. [PDF]

Front Big Data
Terefe EM, Aga MA.
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Capacity building for genomic surveillance of mpox and other emerging diseases in resource-limited settings within the African Great Lakes region. [PDF]

Commun Med (Lond)
Schuele L, Nzoyikorera N, Udahemuka JC, Cassidy H, Murhula Masirika L, Nieuwenhuijse DF, Nduwimana C, Molenkamp R, Nyandwi J, Boter M, Minega Ndoli J, Zaeck LM, Musabyimana JP, de Vries RD, Mbiribindi JB, Siangoli FB, Otani S, Aarestrup FM, Koopmans M, Ndishimye P, Oude Munnink BB.   +20 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Soluble sugar component-based quality assessment and SWEET transport family identification uncovering soluble sugar accumulation mechanism in <i>Zostera marina</i>. [PDF]

Front Plant Sci
Wu M, Liu Y, Li H, Long M, Gao Y, Fu X, Zhang L.   +6 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

The carbon footprint of tourism businesses in Pavlodar region (Kazakhstan): Baseline assessment and decarbonization hot spots. [PDF]

PLoS One
Yessimova D, Belyy A, Faurat A, Novikova-Rodi A, Olshanskaya M, Zavyalova L, Grishchenko I, Yessim A.   +7 more
europepmc   +1 more source