Results 201 to 210 of about 66,320 (342)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
IoT-Based System for Real-Time Monitoring and AI-Driven Energy Consumption Prediction in Fresh Fruit and Vegetable Transportation. [PDF]
Kamyod C +11 more
europepmc +1 more source
Goods Logistics Management Based on the Line Of Transport Operators [PDF]
Yipeng Li, Chunyan Xie
openalex +1 more source
Multimodal transport of goods: regulatory issues
Tyrime yra atliekama multimodalinių krovinių vežimų, kaip teisės instituto, jiems taikytino teisinio reguliavimo ir dėl esamo teisinio reglamentavimo (jo turinio) kylančios problematikos analizė. Tyrime didelis dėmesys skiriamas tarptautinių vienarūšių krovinių vežimo konvencijų taikymo sričiai, analizuojama jų tiesioginio taikymo multimodalinio ...
openaire +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Working donkey welfare assessment and owner survey in Meru County, Kenya. [PDF]
Mellish M, Stull J.
europepmc +1 more source
Energy Intensity in Road Freight Transport of Heavy Goods Vehicles in Spain
L. Andrés, Emilio Padilla
semanticscholar +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Optimization of power grid material warehousing and supply chain distribution path planning based on improved PSO algorithm. [PDF]
Ge J +6 more
europepmc +1 more source

