Results 151 to 160 of about 7,889,263 (337)
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Dynamic fleet management of waterborne vessels with mixed passenger and parcel services
npj Sustainable Mobility and TransportThe integration of mobility and logistics in transport networks offers solutions to urban transportation challenges such as traffic congestion and last-mile delivery.
Heisuke Miyoshi +3 more
doaj +1 more source
Visions for a sustainable transport future: A comparative analysis of transport planning approaches in Singapore, Vienna and Brisbane [PDF]
, 2008 Singapore, Vienna and Brisbane represent three mid-to-large sized metropolitan regions with advanced economies and highly developed societies. On a worldwide basis, Singapore and Vienna are recognised for their enlightened approaches to transport and ...
Charles, Phil, Chris Hale
core
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
On measuring the benefits of lower transport costs [PDF]
Despite large amounts invested in rural roads in developing countries, little is known about their benefits. This paper derives an expression for the willingness-to-pay for a reduction in transport costs from the canonical agricultural household model ...
Jacoby, Hanan G., Minten, Bart
core
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Ridesourcing platforms thrive on socio-economic inequality
Scientific ReportsLimited available market share data seems to suggest that ridesourcing platforms benefit from, even thrive on, socio-economic inequality. We suspect that this is associated with high levels of socio-economic inequality allowing for cheap labour as well ...
Arjan de Ruijter +2 more
doaj +1 more source
Exploring the link between port throughput and economic activity : some comments on space- and time-related issues [PDF]
, 2010 The link between economic activity and (freight) transport is a classic issue in regional science. A subtopic is the impact of economic activity on the demand for maritime transport through ports.
Vanoutrive, Thomas
core +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source