Results 131 to 140 of about 7,889,263 (337)

Road Expansion and Urban Highways: Consequences Outweigh Benefits in Kathmandu [PDF]

, 2017
Rapid urbanization has transformed Kathmandu Valley, Nepal, one of the fastest growing metropolitan regions in South Asia. This urbanization, in turn, is leading to considerable social, economic, and environmental stress.
Chand, Priyankar Bahadur, Gurung, Anobha, Khanal, Prashanta   +2 more
core   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Incorporating Behavioral Adaptation of Human Drivers in Predicting Traffic Efficiency of Mixed Traffic: A Case Study of Priority T-Intersections

European Journal of Transport and Infrastructure Research
As automated vehicles (AVs) are increasingly being deployed on our road network, it becomes important to understand how human drivers interact with them in mixed traffic.
Nagarjun Reddy, Narayana Raju, Haneen Farah, Serge Hoogendoorn   +3 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

A Framework for Synergy Measurement Between Transportation and Production–Living–Ecological Space Using Volume-to-Capacity Ratio, Accessibility, and Coordination

Land
In the stage of high-quality development, the functional coordination between transportation systems and territorial space is a key issue for improving urban spatial efficiency.
Xiaoyi Ma, Mingmin Liu, Jingru Huang, Ruihua Hu, Hongjie He   +4 more
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Cost optimization in the urban distribution of dairy supply – A case of Sanchi, Bhopal, India

Urban, Planning and Transport Research
The study focuses on optimizing urban distribution in the dairy industry, specifically at Bhopal Sanchi dairy, to enhance efficiency and minimize costs. It evaluates existing routes, identifies inefficiencies, and proposes new distribution strategies. By
Ish Kumar, Zeeshan Ahmed, Pankaj Kant
doaj   +1 more source

Optimal treatment planning governed by kinetic equations

, 2009
In this paper we study a problem in radiotherapy treatment planning, where the evolution of the radiation field is governed by a deterministic Boltzmann transport equation.
Frank, Martin, Herty, Michael, Sandjo, Albert N.   +2 more
core  

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source