Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Changing transport planning objectives during the Covid-19 lockdowns: Actions taken and lessons learned for enhancing sustainable urban mobility planning. [PDF]
Kamargianni M +3 more
europepmc +1 more source
The Evolution of Transport Networks [PDF]
Between 1900 and 2000, the length of paved roads in the United States increased from 240 km to 6,400,000 km (Peat 2002, BTS 2002) with virtually 100% of the U.S. population having almost immediate access to paved roadways.
David Levinson
core
Multi-level tensions in transport policy and planning : bus-rapid transit (BRT) in Indonesia : a dissertation presented in fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Planning at Massey University, Palmerston North, New Zealand [PDF]
International development agencies, supporting climate change sensitive transport policies in Low-Income Asian (LIA) cities, promote Bus Rapid Transit (BRT). However, these policies create tensions at the local level.
Wijaya, Suryani Eka
core
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
The COVID-19 pandemic as a starting point to accelerate improvements in health in our cities through better urban and transport planning. [PDF]
Nieuwenhuijsen MJ, Hahad O, Münzel T.
europepmc +1 more source
Linking Smartphone GPS Data with Transport Planning: A Framework of Data Aggregation and Anonymization for a Journey Planning App [PDF]
With the proliferation of GPS tracking data provided by smartphone apps, it is desirable to develop a data processing and anonymizing framework to transform raw GPS data into a suitable format for transport planning models. The paper aims to describe the
McArthur, David Philip, Wang, Yang
core
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Mode use in long-distance travel
This paper focuses on mode use in long-distance travel. Long-distance travel is responsible for more than 50 percent of climate impact. Nevertheless, it is usually excluded from analyses that examine travel behavior. Whereas studies on daily travel prove
Alexander Reichert, Christian Holz-Rau
doaj +1 more source
Models and applications of Optimal Transport in Economics, Traffic and Urban Planning
Some optimization or equilibrium problems involving somehow the concept of optimal transport are presented in these notes, mainly devoted to applications to economic and game theory settings.
Santambrogio, Filippo
core +1 more source

