Results 91 to 100 of about 7,889,263 (337)

Understanding public transit patterns with open geodemographics to facilitate public transport planning

open access: yesTransportmetrica A: Transport Science, 2018
Plentiful studies have discussed the potential applications of contactless smart card from understanding interchange patterns to transit network analysis and user classifications.
Yunzhe Liu, T. Cheng
semanticscholar   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Discovery exhibition: using spatial treemaps in local authority decision making and reporting [PDF]

open access: yes, 2010
At Leicestershire County Council we are using spatial treemaps to analyse labour markets and commuting behaviour. This novel visualization technique, presented at InfoVis 2008, has resulted in a number of insights and discoveries.
Beecham, R.   +4 more
core  

Sustainable Urban Transport Planning Considering Different Stakeholder Groups by an Interval-AHP Decision Support Model

open access: yesSustainability, 2018
Sustainable urban transport requires smart and environmentally-friendly technical solutions. It also needs to meet the demands of different user groups, including current and potential future users, in order to avoid opposition of the citizens and to ...
O. Ghorbanzadeh   +3 more
semanticscholar   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

The Specification of the Planning Systems; Report of the 1993 Questionnaire Survey [PDF]

open access: yes, 1994
This report describes a survey carried out as part of a research project undeaaken hy the Institute for Transport Studies and the School of Computer Studies at the University of Leeds, funded by the Science and Engineering Research Council.
Aldridge, D., Marler, M.W.
core  

stplanr: A Package for Transport Planning

open access: yesThe R Journal, 2018
Tools for transport planning should be flexible, scalable, and transparent. The stplanr package demonstrates and provides a home for such tools, with an emphasis on spatial transport data and non-motorized modes.
R. Lovelace, R. Ellison
semanticscholar   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Modeling Uncertainties for Automated and Connected Vehicles in Mixed Traffic

open access: yesJournal of Advanced Transportation
The advent of automated vehicles (AVs) and connected automated vehicles (CAVs) creates significant uncertainties in infrastructure planning due to many unknowns, such as performance variability and user adaptation. As technologies are still emerging with
Yuchao Sun   +4 more
doaj   +1 more source

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