Results 41 to 50 of about 4,232,368 (304)
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
SIMMAG3D as a tool for designing of storage facilities in 3D [PDF]
Designing of storage facilities is an interdisciplinary process that requires consideration of technical, economic, social or environmental issues. Storage facilities, as a part of supply chain are designed to provide customers availability of goods at a
Marianna Jacyna +2 more
doaj +1 more source
Onset of criticality and transport in a driven diffusive system
We study transport properties in a slowly driven diffusive system where the transport is externally controlled by a parameter $p$.
A. M. Weinberg +6 more
core +1 more source
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
Optimization of delivery routes for takeout under time-varying road networks
Food delivery has emerged as a crucial aspect of the dining experience, driven by the proliferation of the Internet and the expansion of the catering industry. Delivery times have become a significant factor affecting customer satisfaction.
Jiaci Wang +4 more
doaj +1 more source
Scheduling a future air transport system [PDF]
The scheduling of future timetables is an important driver for aircraft sales and design considerations in future aircraft. Airline companies seek to maximise their profits through capturing passenger demand through the quality of service they offer ...
Patel, R.
core
Quantum Transport from the Perspective of Quantum Open Systems
By viewing the non-equilibrium transport setup as a quantum open system, we propose a reduced-density-matrix based quantum transport formalism. At the level of self-consistent Born approximation, it can precisely account for the correlation between ...
Averin +25 more
core +2 more sources
Intestinal macromolecular transport supporting adaptive immunity [PDF]
The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances for the appropriate induction of tolerogenic or protective adaptive immunity.
Kulkarni, Devesha H, Newberry, Rodney D
core +2 more sources
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright +13 more
wiley +1 more source

