Results 41 to 50 of about 239,674 (287)
Energies, 2023 E-scooters as a new form of mobility are gaining more and more popularity. This popularity results from the flexibility of this mode of transport, but above all from the positive impact on the natural environment through the much higher energy efficiency
Elżbieta Macioszek +2 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Evaluating urban freight transport policies within complex urban environments [PDF]
, 2018 Urban Freight Transport (UFT) entails significant advantages for the economic growth of cities, but can also hamper population quality of life, obstructing vehicles and people movements while exacerbating environmental problems.
Benedito Benet, Ernest +3 more
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Estimation of transport accessibility in case of rational transport hub location
Transport, 2021 The public transit accessibility has become an important attribute of social and economic activity of contemporary society. The shift to the sustainable paradigm of the current cities’ development has made public transport the basic mean for population ...
Alexander Rossolov +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Logi, 2023 The purpose of the article is to analyze the technical implementation tools of integrated development of rail and sea transport systems in multimodal transportation in their modern conception.
Lomotko Denis V. +4 more
doaj +1 more source
Energies, 2021 In recent years, policymakers of urban agglomerations in various regions of the world have been striving to reduce environmental pollution from harmful exhaust and noise emissions.
Marianna Jacyna +3 more
doaj +1 more source
Port-City Development: The Spanish Case [PDF]
, 2020 [Abstract]: The objective of this paper is to try to evaluate the port-city relationship from its onset, taking into account the challenges of port 4.0.
Freire Seoane, María Jesús +3 more
core +2 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source