Results 131 to 140 of about 3,725,006 (354)
Cogent Arts & HumanitiesThough the world has witnessed many pandemics so far, this article historicizes the nexus between transportation and pandemics by taking four major pandemics human history has faced so far as representatives. Historically, the means of transportation are
Heena Shrestha, Raj K. Baral*
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The Impact of Autonomous Vehicles on Safety, Economy, Society, and Environment
World Electric Vehicle JournalAutonomous driving is a rising technology expected to revolutionize commuting. Even if the spread of autonomous vehicles is slower than expected some years ago, their progress will not stop and will become a reality shortly.
Luca Gherardini, Giacomo Cabri
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Suicide Bombings Against Trains and Buses Are Lethal but Few [PDF]
, 2015 This Transportation Security Perspective is the sixth in a continuing series produced by the National Transportation Safety and Security Center of the Mineta Transportation Institute.
Butterworth, Bruce R., Jenkins, Brian M.
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Impacts of transportation network companies on urban mobility
Nature Sustainability, 2021 Mi Diao, Hui Kong, Jinhuan Zhao
semanticscholar +1 more source