Results 161 to 170 of about 2,542,719 (338)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Transports internationaux

open access: yes, 2016
En 2017, la croissance du commerce international repart nettement à la hausse et tire la production mondiale Les échanges internationaux de marchandises ont connu en 2017 une croissance de 4,7%, soit un chiffre nettement supérieur aux prévisions les plus optimistes proposées par l'OMC l'année dernière.
openaire   +7 more sources

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Retracted: Discussion on the Construction of Enterprise Internal Audit Informatization

open access: yesJournal of Advanced Transportation, 2023
Journal of Advanced Transportation
doaj   +1 more source

Approach to optimal quantum transport via states over time [PDF]

open access: yesarXiv
We approach the problem of constructing a quantum analogue of the immensely fruitful classical transport cost theory of Monge from a new angle. Going back to the original motivations, by which the transport is a bilinear function of a mass distribution (without loss of generality a probability density) and a transport plan (a stochastic kernel), we ...
arxiv  

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