Results 201 to 210 of about 1,353,338 (294)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
RETRACTION: Refined Judgment of Urban Traffic State Based on Machine Learning and Edge Computing
Journal of Advanced TransportationJournal of Advanced Transportation
doaj +1 more source
Overcoming Transportation Barriers for Low-Income Individuals with Chronic Conditions: Identifying Barriers and Strategies in Access to Healthcare and Food as Medicine (FAM). [PDF]
Healthcare (Basel)Im H +7 more
europepmc +1 more source
RISING ACTION: THE EFFECT OF NARRATIVE TRANSPORTATION ON CONSUMER PURCHASE BEHAVIOR
, 2020 Bryan Samuelsen
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Analyzing Mega-mobility Systems in Smart Cities: A Macro-Micro Integration with Feedback Paradigm Empowered by Artificial Intelligence. [PDF]
Research (Wash D C)Wang Z +10 more
europepmc +1 more source
Railroads of the Raj: Estimating the Impact of Transportation Infrastructure
, 2010 D. Donaldson
semanticscholar +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source