Results 201 to 210 of about 2,898,574 (357)
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Geographic variation in Medicare Advantage nonemergency medical transportation benefits 2020-2024. [PDF]
Lu CA+5 more
europepmc +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Bone transport combined with internal fixation in post-traumatic distal humerus defects and nonunions: retrospective analysis of 16 patients. [PDF]
Kadier X+6 more
europepmc +1 more source
Operating problems of the railroads: Addresses and discussion at transportation meeting held at Mid-Winter Convention of A. I. E. E., Philadelphia, Pa., afternoon of February 5, 1924 [PDF]
L. G. Spooner
openalex +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
2001 WisDOT Specifications - Texture of PCC Pavements [PDF]
Marquette University, Transportation Research Center
core +1 more source
Retracted: Modeling Access to Public Transport in Urban Areas
Journal of Advanced Transportation
doaj +1 more source