Results 221 to 230 of about 2,898,574 (357)

Transport [PDF]

Canadian Medical Association Journal, 2015
openaire   +2 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Presence of Institutional Guidance on Research-Related Transportation Could Help Reduce Barriers to and Disparities in Research Engagement. [PDF]

J Clin Transl Sci
Prestayko N, Ossorio PN, Fisher A, Menon N, Downs DS, Yerby LG, Zgierska AE.   +6 more
europepmc   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Effect of transport stress on apoptosis and autophagy in goat lung cells. [PDF]

Front Vet Sci
Zhuo Y, Hu Y, Jin Y, Ye T, Yang Y, Liu B, Zheng W, Ding S, Yang X, Zheng L, Hu W, Fang M, Yi W, Xing W.   +13 more
europepmc   +1 more source

Horse packing : a manual of pack transportation

, 1914
Charles Johnson Post
openalex   +2 more sources

Discussion: “Railway Practice in Utilization and Conservation of Coal: With a Fuel Cost for Transportation of Over a Million Dollars a Day, the Roads Have Followed the Concerted Efforts Begun During the War With a Large Further Reduction” (Overmire, W. J., 1928, Trans. ASME, 49–50(3), p. 031074) [PDF]

, 1928
J. G. Crawford, W. J. Overmire
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Transportation Economics [PDF]

J. R. Meyer, M. J. Peck
core   +6 more sources

Constructing the commuting backbone network dataset for the United States. [PDF]

Sci Data
Wang J, Hu Y.
europepmc   +1 more source