Results 151 to 160 of about 5,497,503 (307)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The transportation economy : just in time. [PDF]

DTRT06-G-0044The purpose of this project was to produce a short educational video, targeted at middle school and high school students, illustrating the critical role transportation plays in our modern economy.
Cole, Richard, Texas Transportation Institute. University Transportation Center for Mobility, Dennis, David   +2 more
core  

Maritime trade and transportation '99

The marine transportation system contributes to U.S. economic growth, enhances global competitiveness, and supports national security objectives.
United States. Department of Transportation. Bureau of Transportation Statistics
core   +1 more source

The effect of the China-Thailand railway on Thailand's trade with China Guangxi Province. [PDF]

PLoS One
Wei S, Xia L.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

SLRV Engineering Tests at Department of Transportation Transportation Test Center: Volume II--Performance and Power Consumption Tests

DOT-TSC-1062The SLRV (Standard Light Rail Vehicle) is a 71-foot vehicle, articulated to negotiate curves down to 32-foot radius and designed to operate at speeds up to 50 mph.
Boeing Vertol Company, John A. Volpe National Transportation Systems Center (U.S.)   +1 more
core   +1 more source

Thermal Performance of ternary hybrid nanofluid with activation energy and surface tension gradient using HCM and YOM models. [PDF]

Discov Nano
Ettoumi M, Safra I, Secer A, Rakhmonov F, Kanwal S.   +4 more
europepmc   +1 more source

Engineering and Transport [PDF]

Nature, 1937
openaire   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

CIVIL ENGINEERING STUDIES : Illinois Center for Transportation Series No. 10-071 [PDF]

The Illinois Department of Transportation (IDOT) and the Illinois Center for Transportation (ICT) sponsored andhosted the first National Safety Performance Function Summit on July 29 and 30, 2009, in Chicago, Illinois.
Ouyang, Yanfeng, Illinois Center for Transportation   +1 more
core