Results 201 to 210 of about 487,951 (354)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Perspectives of Community Health Center Employees on Public Bus Transportation in Rural Hawai'i County. [PDF]

Int J Environ Res Public Health
Keliikoa LB, Hartz C, Pontalti A, Reelitz K, Hansen Smith H, Otsuka K, Ching LK, McGurk MD.   +7 more
europepmc   +1 more source

Oxygenation Status, Prehospital Communication, and Mode of Transportation for Critically Ill Patients: A Cross-Sectional Study in Addis Ababa Hospitals [PDF]

Mahlet Birhane
openalex   +1 more source

Transportation Access to Health Care During the COVID-19 Pandemic: Trends and Implications for Significant Patient Populations and Health Care Needs

, 2020
Katherine L. Chen
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The air transport of patients.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975
Air transport of patients by light aircraft and air ambulance is safe, fast and comfortable, and it is becoming increasingly popular. There are, however, specific problems, shortcomings and other details which must be dealt with effectively at various levels to ensure the best service for the patient.
openaire   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Trends in Varying Modes of Hospital Arrival: What Determines the Ideal Mode of Transportation? [PDF]

Cureus
Gelis AW, Henken-Siefken A, McCague A.
europepmc   +1 more source

Life-sustaining measures at the expense of the prehospital nurse s safety : An interview study on the prehospital nurse s experience of ventilating patients during ambulance transportation

, 2020
Lindström, Fredrik, Hedlund, Fredrik
openalex   +1 more source