Results 51 to 60 of about 487,951 (354)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Functioning and disability in multiple sclerosis from the patient perspective [PDF]

, 2011
Multiple sclerosis (MS) has a great impact on functioning and disability. The perspective of those who experience the health problem has to be taken into account to obtain an in-depth understanding of functioning and disability.
Alarcos Cieza, Birgit Basedow-Rajwich, Cieza A, Denzin N, Folstein M, Jürg Kesselring, Karlsson G, Kvale S, Michaela Coenen, Nicolaus König, Patton MQ, Simioni S, Stuifbergen A, World Health Organisation   +13 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Optimization of Intrahospital Transportation of Cardiosurgical Patients

Общая реаниматология, 2007
Objective: to optimize the transportation of cardiosurgical patients from the operating-room to an intensive care unit (ICU), by developing and introducing a pathogenetically grounded measure to prevent poor circulatory reactions.Materials and methods ...
I. A. Kozlov, G. V Korosteleva, I. Yu. Tyunyaeva, A. Ye. Yermolenko, V. V. Ilnitsky   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Healthcare Cost Savings Through Telemedicine Use At Correctional State Facilities [PDF]

, 2018
Telemedicine offers both soft and hard return on investment, including cost savings avoidance and convenience of access to care. Incarcerated individuals represent a patient population that uniquely benefit from receiving care via telemedicine.
Broadnax, Tamara, Collins, David, Davis, Sydney, Mishra, Vimal, Mui, Paulius   +4 more
core   +1 more source

INTERHOSPITAL TRANSPORT OF THE HIGH-RISK NEWBORN: A CHALLENGE FOR THE NURSING STAFF

Cogitare Enfermagem, 2016
This study aimed to investigate the conditions in which the interhospital transport of high-risk newborns takes place, between their municipality of origin and the Mother and Child Hospital in Belo Horizonte, in the Brazilian State of ...
Paula Cristina de Oliveira Pimenta, Valdecyr Herdy Alves   +1 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Point of Care Technology for Underserved Populations [PDF]

, 2017
Point of Care technology is an emerging healthcare field. This technology allows for rapid, inexpensive, on-site testing for otherwise lengthy and costly laboratory tests. Leading infectious diseases can be tested immediately in non-invasive ways similar
Maloney, Anna
core   +1 more source