Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
CRISPR-based genome editing reveals the roles of efflux pumps in <i>Mycobacterium abscessus</i>. [PDF]
Li S +7 more
europepmc +1 more source
Expression of SOD1 G93A or wild‐type SOD1 in primary cultures of astrocytes down‐regulates the glutamate transporter GLT‐1: lack of involvement of oxidative stress [PDF]
Massimo Tortarolo +6 more
openalex +1 more source
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Exploring structural, functional, evolutionary, and genetic characteristics of sugar transporters in maize and their roles in abiotic stress tolerance. [PDF]
Mia MS +10 more
europepmc +1 more source
Syntaxin 4 Expression Affects Glucose Transporter 8 Translocation and Embryo Survival [PDF]
Amanda Wyman +7 more
openalex +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Identification of transporters essential for survival of Leishmania promastigotes in the digestive tract of sand flies. [PDF]
Sádlová J +9 more
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Frontiers in cadmium mitigation: harnessing Nitrate Transporter 1 (NRT1) for plant systems. [PDF]
Marques DN, Azevedo RA.
europepmc +1 more source

