Results 191 to 200 of about 981,318 (341)

Transmembrane Transport of cAMP and AMP Using a Two Component Small Molecule Transport System. [PDF]

Angew Chem Int Ed Engl
Rathnaweera UMC, Sam O, Norvaisa K, Marshall SR, Weerakonda Arachchige RDS, Chvojka M, Valkenier H, Busschaert N.   +7 more
europepmc   +1 more source

In Vitro and in Vivo Characterization of Bosutinib as Substrate of the Pglycoprotein Efflux Transporter

, 2014
Sara Redaelli, Pietro Perini, Monica Ceccon, Rocco Piazza, R Rigolio, Frank Boschelli, Athina Giannoudis, Carlo Gambacorti‐Passerini   +7 more
openalex   +1 more source

Author response: Allosteric effects of the coupling cation in melibiose transporter MelB [PDF]

Parameswaran Hariharan, Yuqi Shi, Rosa Viner, Lan Guan   +3 more
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Gut Microbiota in the Regulation of Intestinal Drug Transporters: Molecular Mechanisms and Pharmacokinetic Implications. [PDF]

Int J Mol Sci
Rzeczycki P, Pęciak O, Plust M, Droździk M.   +3 more
europepmc   +1 more source

Characterization and inhibition of human and plasmodial lactate transporters with particular special consideration of the pentafluoro-3-hydroxy-pent-2-en-1-one

, 2021
Walloch, Philipp
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Old Drug, New Science: Metformin and the Future of Pharmaceutics. [PDF]

Pharmaceutics
Caturano A, Nilo D, Nilo R, Sircana MC, Erul E, Zielińska K, Russo V, Santonastaso E, Sasso FC.   +8 more
europepmc   +1 more source

Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium.

, 1994
Kari J. Buck, Susan Amara
openalex   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source