Results 201 to 210 of about 981,318 (341)

Dopamine transporter mutant animals: a translational perspective

, 2016
Evgeniya V. Efimova, Raul R. Gainetdinov, Evgeny A. Budygin, Tatyana D. Sotnikova   +3 more
openalex   +2 more sources

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Transport of the abundant intestinal amino acid glutamine by the enteric pathogen <i>Campylobacter jejuni</i> occurs via GutA (Cj0903), an AGCS family transporter. [PDF]

Microbiology (Reading)
Griffin A, Whitmore JK, Sharp C, Webb JP, Bennison DJ, Corrigan RM, Kelly DJ, Taylor AJ.   +7 more
europepmc   +1 more source

Use of a Selective Inhibitor To Define the Chemotherapeutic Potential of the Plasmodial Hexose Transporter in Different Stages of the Parasite's Life Cycle

, 2011
Ksenija Slavić, Michael J. Delves, Miguel Prudêncio, Arthur M. Talman, Ursula Straschil, Elvira T. Derbyshire, Zhengyao Xu, Robert E. Sinden, Maria M. Mota, Christophe Morin, Rita Tewari, Sanjeev Krishna, Henry M. Staines   +12 more
openalex   +2 more sources

Frontal-Limbic White Matter Pathway Associations with the Serotonin Transporter Gene Promoter Region (5-HTTLPR) Polymorphism [PDF]

, 2009
Jennifer Pacheco, Christopher G. Beevers, Cristina Benavides, John E. McGeary, Eric Stice, David M. Schnyer   +5 more
openalex   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis

, 2016
Lalit K. Golani, Adrianne Wallace-Povirk, S.M. Deis, Jennifer Wong-Roushar, Jiyuan Ke, Xin Gu, Sudhir Raghavan, Mike R. Wilson, Xinxin Li, Lisa Polin, Parker W. de Waal, Kathryn White, Juiwanna Kushner, Carrie O’Connor, Zhanjun Hou, H. Eric Xu, Karsten Melcher, Charles E. Dann, Larry H. Matherly, Aleem Gangjee   +19 more
openalex   +2 more sources

Impaired glucose homeostasis, neutrophil trafficking and function in mice lacking the glucose-6-phosphate transporter [PDF]

, 2003
Li Yuan Chen
openalex   +1 more source

Dynamics of Adaptive Microevolution of Hypermutable Pseudomonas aeruginosa during Chronic Pulmonary Infection in Patients with Cystic Fibrosis [PDF]

, 2009
Eichner, Anja, Heesemann, Jürgen, Henke, Chrstine, Hoboth, Christina, Hoffmann, Reinhard, Hogardt, Michael, Imhof, Axel, Schmold, Sabine   +7 more
core   +1 more source

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source