Results 151 to 160 of about 32,498 (309)

[The future of public health after the pandemic. A window of opportunity]. [PDF]

An Sist Sanit Navar, 2023
Peiró S.
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

PRIVATIZAÇÃO EM TRANSPORTES: CAVALO DE TRÓIA?

, 2010
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Willian Alberto de Aquino Pereira
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Time of day is associated with federal highway accidents in Brazil. [PDF]

Braz J Med Biol Res
Parro VC, Moreno CRC, Folkard S, Cardoso LB, Gueter DDV, Mesquita PGJ.   +5 more
europepmc   +1 more source

Energy solvency. A new concept to prevent energy poverty in Spain. [PDF]

Energy Effic, 2022
Gallego Sánchez-Torija J, Fernández Nieto MA, Gómez Serrano PJ.   +2 more
europepmc   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

[In defense of walking and cycling as a means of transportation in Brazil]. [PDF]

Cad Saude Publica
Florindo AA, Goulardins GS, Andrade DR, Knebel MTG, Santos MP, Hallal PC, Mota J.   +6 more
europepmc   +1 more source

Improvement of Warm-Mix Asphalt Concrete Performance with Lignin Obtained from Bioethanol Production from Forest Biomass Waste. [PDF]

Materials (Basel), 2023
Pascoal A, Almeida A, Capitão S, Picado-Santos L.   +3 more
europepmc   +1 more source