Results 121 to 130 of about 7,396,251 (305)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Covid-19, un avenir toujours incertain qui invite à surtout ne pas baisser les bras. [PDF]
Bull Acad Natl Med, 2022 europepmc +1 more source
CONTROLER LA QUALITE DES SERVICES PUBLICS : QUELLE PLACE POUR LES USAGERS ?: Etude de deux expériences de collectivités territoriales françaises [PDF]
, 2013 International audienceFrench local services analysis shows an increasing interest to service user. Management control systems are developed in order to improve service quality and adaptation to users 'needs. However, user's place is not so obvious.
Ragaigne, Aurélien, Tahar, Caroline
core +4 more sources
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Convivialité des municipalités canadiennes à l'égard des aînés : portrait et facteurs associés. [PDF]
Can J Public Health, 2022 St-Pierre C +3 more
europepmc +1 more source
Étude sur la dynamisation du covoiturage en entreprise au sein d'un plan de déplacement inter-entreprise [PDF]
, 2014 Le covoiturage domicile-travail est une pratique de covoiturage à part entière, extrêmement différente du covoiturage ponctuel popularisé par le succès de Blablacar.
Faessel, Julien
core
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source