Results 31 to 40 of about 43,431 (260)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Financing urban transport through value capture. [PDF]

, 2010
The Green Paper on Urban Transport highlights the importance of promoting public transport as a means of achieving better sustainable mobility. Unfortunately, budget resources are often constrained. On the other hand, literature points out that transport
Mejía Dorantes, Lucía, Vassallo Magro, José Manuel   +1 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Du citoyen et de la « civilité ». Réflexions à partir de l’exemple de la vidéosurveillance

Lien Social et Politiques, 2007
Dans la foulée des événements du 11 septembre 2001, la problématique des incivilités permet de légitimer des politiques sécuritaires souvent musclées. Comment cette situation influence-t-elle les relations entre l’État et le citoyen ?
Jean Ruegg, Francisco Klauser, Valérie November   +2 more
doaj   +1 more source

Des aménagements piétons pour un accès plus attractif aux transports publics ? Une approche comparative franco-tchèque. [PDF]

, 2014
Cette communication s'inscrit dans le champ des recherches portant sur la conception d'espaces urbains à l'échelle de quartier et adaptés à l'usage des transports collectifs, champ habituellement qualifié d'" urbanisme orienté vers les transports ...
Mermet, Samuel, Smida, Jiri, Zelezny, Richard   +2 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Transports publics et taxis : concurrence ou complémentarité ? [PDF]

, 2010
Loin d'être concurrents, taxis et transports collectifs sont souvent complémentaires, les collectivités locales, qui subventionnent leur réseau de transports collectifs, font souvent des économies en confiant à des taxis plutôt qu'à des services ...
Darbéra, Richard
core   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Exploitation de l'imagerie Pléiades-THR en cartographie réactive suite à des catastrophes naturelles ayant affecté le territoire français en 2013

Revue Française de Photogrammétrie et de Télédétection, 2015
Dans le cadre de la Recette Thématique Utilisateur pour la valorisation des données Pléiades-THR, des images ont été acquises lors de désastres naturels ou pour des exercices dédiés à la demande des grands services de l'Etat (Ministère de l'Environnement,
Hervé Yésou, Aurélie Escudier, Stéphanie Battiston, Jean-Yves Dardillac, Stephen Clandillon, Carlos Uribe, Mathilde Caspard, Henri Giraud, Jérôme Maxant, Arnaud Durand, Kader Fellah, Mathias Studer, Claire Huber, Laurent Philippoteaux, Paul de Fraipont, Delphine Fontannaz   +15 more
doaj   +1 more source