Results 81 to 90 of about 7,396,251 (305)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Brussels StudiesThis paper investigates the gap in PT access to the city faced by disabled people when using public transport in Brussels. The research is carried out at the route level from all STIB-MIVB stops to 20 selected destinations across the city.
Frédéric Dobruszkes +2 more
doaj +1 more source
Evaluation économique de la mise en place de la cardiologie interventionnelle dans le canton de Fribourg : analyse de minimisation des coûts du point de vue du canton en tant que payeur dans le système sanitaire [PDF]
, 2006 [...] Le but du présent travail est d'analyser pour le canton [de Fribourg] en tant que payeur dans le système de santé, les incidences financières de la probable mise en place d'un service de cardiologie interventionnelle à l'Hôpital cantonal de ...
Marchioni, Patrick
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Toward Sustainable Mobility: AI-Enabled Automated Refueling for Fuel Cell Electric Vehicles
EnergiesWith the global transportation sector being a major contributor to greenhouse gas (GHG) emissions, transitioning to cleaner and more efficient forms of transportation is essential for mitigating climate change and improving air quality.
Sofia Polymeni +6 more
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
On losing the "dispensable" sense: TikTok imitation publics and COVID-19 smell loss challenges. [PDF]
Media Cult Soc, 2023 Michell AG.
europepmc +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The determinants of urban public transport: an international comparison and econometric analysis [PDF]
The analysis presented in this paper is based on the database created by the UITP (International Association of Public Transport), "The Millennium Cities Database", which covers the public transport systems in 100 of the world's cities.
Iragaël Joly +2 more
core
La mairie de Londres: l'exception qui confirme la règle [PDF]
, 2004 Le maire de Londres se fie à l'efficacité lorsque le service répond aux exigences du service citoyen plutôt qu'à des questions de simple rentabilité. Il protège ainsi une certaine éthique du service public et se dresse comme un rempart contre ceux qui ...
Whitton, Timothy
core +1 more source