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Transposable elements as genomic diseases [PDF]
Human disease agents can get transmitted both horizontally--through infection--and vertically--from parent to offspring. Depending on details of their evolutionary dynamics, they may increase or decrease in virulence over time.
Wagner, A
core +5 more sources
RepetDB: a unified resource for transposable element references
Background Thanks to their ability to move around and replicate within genomes, transposable elements (TEs) are perhaps the most important contributors to genome plasticity and evolution.
Joëlle Amselem+11 more
doaj +2 more sources
Mapping of important taxonomic and productivity traits using genic and non-genic transposable element markers in peanut (Arachis hypogaea L.). [PDF]
A mapping population of recombinant inbred lines (RILs) derived from TMV 2 and its mutant, TMV 2-NLM was employed for mapping important taxonomic and productivity traits using genic and non-genic transposable element markers in peanut.
Anil A Hake+10 more
doaj +2 more sources
Transposable element landscapes in aging Drosophila.
Genetic mechanisms that repress transposable elements (TEs) in young animals decline during aging, as reflected by increased TE expression in aged animals. Does increased TE expression during aging lead to more genomic TE copies in older animals?
Nachen Yang+9 more
doaj +3 more sources
Transposable elements in Drosophila [PDF]
AbstractDrosophila has been studied as a biological model for many years and many discoveries in biology rely on this species. Research on transposable elements (TEs) is not an exception. Drosophila has contributed significantly to our knowledge on the mechanisms of transposition and their regulation, but above all, it was one of the first organisms on
Mérel, Vincent+3 more
openaire +6 more sources
Pathogenic Tau Accelerates Aging-Associated Activation of Transposable Elements in the Mouse Central Nervous System [PDF]
Transposable elements comprise almost half of the mammalian genome. A growing body of evidence suggests that transposable element dysregulation accompanies brain aging and neurodegenerative disorders, and that transposable element activation is ...
Beckmann, Adrian+13 more
core +2 more sources
Transposable element-mediated rearrangements are prevalent in human genomes
Here the authors show that transposable element-mediated rearrangements impact more than 500 kbp of an average human genome, are a source of individual variation, a substrate for evolutionary change, and can occur through diverse mechanisms. Transposable
Parithi Balachandran+5 more
semanticscholar +1 more source
Transposable elements (TEs) make up a majority of a typical eukaryote’s genome, and contribute to cell heterogeneity in unclear ways. Single-cell sequencing technologies are powerful tools to explore cells, however analysis is typically gene-centric and ...
Jiangping He+11 more
semanticscholar +1 more source
Transposable elements (TEs) help shape the structure and function of the human genome. When inserted into some locations, TEs may disrupt gene regulation and cause diseases.
Chong Chu+6 more
semanticscholar +1 more source
Rose (Rosa sp.) flowers have a rich diversity of colors resulting from the differential accumulation of anthocyanins, flavonols, and carotenoids. However, the genetic and molecular determinants of the red-petal trait in roses remains poorly understood ...
Maofu Li+27 more
doaj +1 more source