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Transposable elements (TEs) help shape the structure and function of the human genome. When inserted into some locations, TEs may disrupt gene regulation and cause diseases.
Chong Chu+6 more
semanticscholar +1 more source
Whole genome resequencing reveals natural target site preferences of transposable elements in Drosophila melanogaster. [PDF]
Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity.
Raquel S Linheiro, Casey M Bergman
doaj +1 more source
Transposable elements (TEs) make up a majority of a typical eukaryote’s genome, and contribute to cell heterogeneity in unclear ways. Single-cell sequencing technologies are powerful tools to explore cells, however analysis is typically gene-centric and ...
Jiangping He+11 more
semanticscholar +1 more source
RepeatModeler2 for automated genomic discovery of transposable element families
Significance Genome sequences are being produced for more and more eukaryotic species. The bulk of these genomes are composed of parasitic, self-mobilizing transposable elements (TEs) that play important roles in organismal evolution.
Jullien M. Flynn+6 more
semanticscholar +1 more source
TnCentral: a Prokaryotic Transposable Element Database and Web Portal for Transposon Analysis
The ability of bacteria to undergo rapid evolution and adapt to changing environmental circumstances drives the public health crisis of multiple antibiotic resistance, as well as outbreaks of disease in economically important agricultural crops and ...
K. Ross+8 more
semanticscholar +1 more source
Rose (Rosa sp.) flowers have a rich diversity of colors resulting from the differential accumulation of anthocyanins, flavonols, and carotenoids. However, the genetic and molecular determinants of the red-petal trait in roses remains poorly understood ...
Maofu Li+27 more
doaj +1 more source
Genomic impact of stress-induced transposable element mobility in Arabidopsis
Transposable elements (TEs) have long been known to be major contributors to plant evolution, adaptation and crop domestication. Stress-induced TE mobilization is of particular interest because it may result in novel gene regulatory pathways responding ...
D. Roquis+5 more
semanticscholar +1 more source
Transposable element invasions [PDF]
Transposable elements have an ongoing, largely parasitic interaction with their hosts. We are interested in the timescale of this interaction. In a recent publication, we have examined the sequence divergence between class II DNA transposons from mammalian genomes.
Elizabeth Hellen, John F. Y. Brookfield
openaire +3 more sources
The CCCTC-binding factor (CTCF) of Drosophila contributes to the regulation of the ribosomal DNA and nucleolar stability. [PDF]
In the repeat array of ribosomal DNA (rDNA), only about half of the genes are actively transcribed while the others are silenced. In arthropods, transposable elements interrupt a subset of genes, often inactivating transcription of those genes. Little is
Paola A Guerrero, Keith A Maggert
doaj +1 more source
Structural differences between genomes are a major source of genetic variation that contributes to phenotypic differences. Transposable elements, mobile genetic sequences capable of increasing their copy number and propagating themselves within genomes ...
Manisha Munasinghe+8 more
doaj +1 more source