Results 191 to 200 of about 68,477 (364)

Remodeling protein complexes: Insights from the AAA+ unfoldase ClpX and Mu transposase [PDF]

, 2005
Briana M. Burton, Tania A. Baker
openalex   +1 more source

Analysis of DNA transposition by DNA transposases in human cells [PDF]

, 2023
Yves Bigot, Makiko Yamada, Helen Mueller, Victor O. Morell, Sabine Alves, Thierry Lecomte, Alex Kentsis   +6 more
openalex   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

Cell Proliferation, EarlyView.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang, Qizhi Wang, Yu Wu, Chen Gu, Mingfei Li, Yong Fan, Xiangjin Kang, Lei Li, Zheng Gao, Mingyan Hei, Jianqiao Liu, Lei Li   +11 more
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Flexibility in MuA Transposase Family Protein Structures: Functional Mapping with Scanning Mutagenesis and Sequence Alignment of Protein Homologues

, 2012
Tiina Rasila, Mauno Vihinen, Lars Paulín, Saija Haapa-Paananen, Harri Savilahti   +4 more
openalex   +2 more sources

Mutational analysis of theattDNA-binding domain of phage Mu transposase [PDF]

, 1995
Keetae Kim, Rasika M. Harshey
openalex   +1 more source

Independent evolution of transposase and TIRs facilitated by recombination between Mutator transposons from divergent clades in maize [PDF]

, 2023
Charles T. Hunter, Donald R. McCarty, Karen E. Koch   +2 more
openalex   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery [PDF]

, 2012
Melanie Galla, Axel Schambach, Christine S. Falk, Tobias Maetzig, Johannes Kuehle, Kathrin Lange, Daniela Zychlinski, Niels Heinz, Martijn H. Brugman, Gudrun Göhring, Zsuzsanna Izsvák, Zoltán Ivics, Christel Baum   +12 more
openalex   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source