Results 41 to 50 of about 265,737 (174)

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Hidden charm mesons in nuclear matter and nuclei

, 2022
Recent results for the ηc- and J/ψ-nucleus bound state energies for various nuclei are presented. The attractive potentials for the ηc and J/ψ mesons in the nuclear medium originate, respectively, from the in-medium enhanced DD∗ and DD¯ loops in the ηc ...
Tsushima, K., K. Tsushima, A.W. Thomas, G. Krein, Krein, G., Javier Cobos Martinez, Cobos Martínez, J.J., Thomas, A.W.   +7 more
core   +1 more source

Current strategies to enhance the target efficiency of advanced multifunctional ultrasound contrast agents in ischemic diseases

Interdisciplinary Medicine, EarlyView.
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou, Jing Lin, Yu Chen, Jiaqi Zhao   +3 more
wiley   +1 more source

Structural Covariance Analysis of Altered Brain Development in Neonates With Congenital Heart Disease After Surgery

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Brain development is altered in neonates with congenital heart disease (CHD), with well‐characterised reductions in regional brain volumes and enlargement of CSF spaces. However, perioperative morphological changes remain incompletely understood. Purpose To identify brain regions showing spatial patterns of coordinated expansion and
Mirthe E. M. van der Meijden, Barat Gal‐Er, Benjamin Clayden, Siân Wilson, Daniel Cromb, Andrew T. M. Chew, Alexia Egloff, Kuberan Pushparajah, John Simpson, Joseph V. Hajnal, A. David Edwards, Mary Rutherford, Jonathan O'Muircheartaigh, Serena J. Counsell, Alexandra F. Bonthrone   +14 more
wiley   +1 more source

Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues [PDF]

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Darren K Griffin, Foster, H, Bridger Joanna M, Bridger, JM, Foster Helen A, Griffin, DK, Foster, Helen A., Bridger, Joanna M., Joanna M Bridger, Helen A Foster, Griffin Darren K, Griffin, Darren K.   +11 more
core   +1 more source

Simulation of the Rotational Molding Process of Polyethylene Using the Smoothed Particle Hydrodynamics Method

Polymer Engineering &Science, EarlyView.
Numerical simulation of polyethylene rotational molding using the Smoothed Particle Hydrodynamics (SPH) method. ABSTRACT This work presents the development of a numerical model based on the smoothed particle hydrodynamics (SPH) method to simulate the rotational molding process of powder thermoplastic polymers, used in the manufacture of liners for high‐
Ali Nourreddine, Albert Lucas, Séverine Boucaud‐Gauchet, Abbas Tcharkhtchi, Sofiane Khelladi   +4 more
wiley   +1 more source

Gene turnover in the common ancestor of all C4 grasses

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira, Ahmed S. Alenazi, Sahr Mian, Ilia J. Leitch, Pascal‐Antoine Christin, Colin P. Osborne, Luke T. Dunning   +6 more
wiley   +1 more source

A Review on Jahn–Teller Distortions in Prussian Blue Analogs Molecular Magnets

The Chemical Record, EarlyView.
This review highlights the central role of the Jahn–Teller effect in governing structural stability and electrochemical performance in Prussian blue analogs (PBAs). It establishes clear structure–property relationships and summarizes effective mitigation strategies, providing design guidelines for developing stable, high‐performance PBA‐based energy ...
Nilasha Maiti, Sher Singh Meena, Pramod Bhatt   +2 more
wiley   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

Decoding neuronal vulnerability: Multidimensional analysis of D1R‐ and D2R‐ medium‐sized spiny neurons in Huntington's disease

Brain Pathology, EarlyView.
D1R and D2R MSNs show distinct responses to Huntington's pathology. G&T‐sequencing of pre‐symptomatic MSNs reveals global LINE‐1 downregulation. While D1R‐MSNs display early transcriptomic changes (OXPHOS/translation upregulation) and reduced mutant huntingtin aggregation, D2R‐MSNs exhibit higher nuclear mHTT accumulation and greater CAG somatic ...
Guendalina Bergonzoni, Miguel Pellegrini, Aurora Savino, Martina Lazioli, Sarah Geurs, Lorenzo Graziani, Denise Ferrarini, Solaleh Khoramian Tusi, Esaria Oliver, Jarne Geurts, Sara Vinciguerra, Michele Tebaldi, Takshashila Tripathi, Isabella Pesce, Valeria Poli, Alessandro Romanel, Rosario Moratalla, Thierry Voet, Jasmin Morandell, Remo Sanges, Vanessa C. Wheeler, Erik Dassi, Marta Biagioli   +22 more
wiley   +1 more source