Results 81 to 90 of about 2,148 (146)
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
The Plant Genome, Volume 19, Issue 1, March 2026.Abstract Oxalis oulophora, a diploid species closely related to the octoploid Andean tuber crop oca (Oxalis tuberosa), was selected for whole‐genome sequencing to aid in understanding the origins of polyploidy and domestication in oca and its relatives (crop wild relatives).
Dilrini Vanrooyen, Eve Emshwiller
wiley +1 more source
Evolution &Development, Volume 28, Issue 1, March 2026.doublesex regulates sexual dimorphism in elytral color patterns of Harmonia axyridis by downregulating the color patterning gene h in males. This regulatory link diverged in derived color morphs, coinciding with the loss of sex‐specific elytral color patterns.
Soichi Yeki +7 more
wiley +1 more source
Advanced Science, Volume 13, Issue 7, 3 February 2026.Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo +6 more
wiley +1 more source
Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication
Advanced Science, Volume 13, Issue 8, 9 February 2026.EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu +12 more
wiley +1 more source
Advanced Science, Volume 13, Issue 7, 3 February 2026.In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei +9 more
wiley +1 more source
Targeting cell-derived markers to improve the detection of invisible biological traces for the purpose of genetic-based criminal identification. [PDF]
Sci Rep, 2023 Recipon M +8 more
europepmc +1 more source
Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.1. Haplo+cord HSCT yields superior survival compared with single cord HSCT in patients with R/R leukaemia. 2. Single‐cell RNA‐seq revealed a functionally critical CD8⁺ T cell population, with cytotoxic and memory phenotypes, which expands after haplo+cord HSCT and tracks with prolonged survival. 3. Multi‐omics profiling at single‐cell resolution showed
Hua Li +18 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.(1) Core Process: Persistent antigen, from TDLNs to TME, drives Tpex → Tex‐int → Tex‐term differentiation. (2) Multiomics Regulation: This fate transition is orchestrated by a co‐ordinated, multi‐layered molecular network. (3) Functional Outcome: Dysregulated signalling and surging co‐inhibitory receptors lock in proliferative arrest and functional ...
Tong Zhu +5 more
wiley +1 more source
European Journal of Immunology, Volume 56, Issue 2, February 2026.A deeper understanding of the natural killer cell gene expression regulation driving NK cell maturation and cytotoxicity could provide critical insights into optimizing NK therapies. Our findings reveal novel enhancers governing NK cell genes for NCAM1/CD56 and cis‐regulation for KIR receptors and clarify existing models of NK cell cis‐accessibility ...
Mariam A. Salem +9 more
wiley +1 more source