Results 101 to 110 of about 124,783 (317)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

“As a chief needs men, so men need a chief” [PDF]

open access: yes, 2015
Since the eighteenth century, the role of the orchestra conductor has continuously evolved in step with changes in the social world. But the authority figure the conductor has represented since the historic greats remains deeply engraved in our ...
Céline Lambeau, Lambeau, Céline
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Adaptation of the AFLP technique as a new tool to detect genetic instability and transposition in interspecific hybrids

open access: yesBioTechniques, 2011
An adapted amplified fragment length polymorphism (AFLP) protocol is presented for detection of hybrid instability in the genome of interspecific hybrids between Drosophila buzzatii and D. koepferae species.
Doris Vela   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Aimée Boutin, City of Noise: Sound and Nineteenth-Century Paris [PDF]

open access: yes, 2019
City of Noise is doubtlessly a groundbreaking contribution to the study of historical urban soundscapes in modern cities. The book takes significant steps towards understanding the complex relationship between, on one hand, the different sound practices ...
Llano, Samuel, Samuel Llano
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Jane F. Fulcher, Renegotiating French Identity: Musical Culture and Creativity in France During Vichy and the German Occupation [PDF]

open access: yes, 2019
This book is the fourth installment in Jane Fulcher’s ambitious, chronologically-organized project of examining music in France and the way that it has been created, interpreted, understood and deployed within ever-shifting political contexts.
Christopher Moore, Moore, Christopher
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Captiver/séduire. Note sur la gestuelle des joueurs de hautbois nāgasvaram [PDF]

open access: yes, 2012
Le jeu du hautbois nāgasvaram fait appel à des gestes qui n’interviennent pas directement dans la production du son : l’instrument, en effet, est régulièrement mis en mouvement, verticalement, horizontalement, ou en combinant ces deux plans.
William Tallotte, Tallotte, William
core   +1 more source

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