Results 81 to 90 of about 84,372 (267)

Treatment of Maxillary Canine and Premolar Transposition: Case Report

open access: yesTurkish Journal of Orthodontics, 2009
Transposition is a dental anomaly manifested by a positional interchange of 2 adjacent teeth within the same quadrant of dental arch. The most frequent tooth transposition seen in the literature is maxillary canine-first premolar [Mx4-3] transposition ...
Oral Sökücü, Ruhi Nalçacı
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Les problèmes d’ordre lexical dans Mon cher fils de Leïla Sebbar المشكلات المعجمية في رواية ابني العزيز للكاتبة ليلي سيبار

open access: yesمجلة کلية الآداب. جامعة أسوان
La traduction est bien plus qu’un simple passage d’une langue à une autre. Elle est un acte de médiation culturelle, une passerelle entre les peuples, les sociétés et les imaginaires. Traduire un texte littéraire, c’est transmettre une voix, une émotion,
Walaa El Nagar Fayez
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Un modèle praxéologique et institutionnel

open access: yesContextes et Didactiques
C. Castela’s article in this issue concludes by suggesting that ontologies, as well as certain aspects of indigenous knowledge, are destined to become part of processes of circulation toward other cultures and of universalization, for the greater good of
Corine Castela, Avenilde Romo Vázquez
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

“Boggy, Soggy, Squitchy Pictures”: Adaptations of Moby-Dick in the Art of Jean-Michel Basquiat

open access: yesNalans
Throughout the twentieth century, Moby-Dick has inspired countless visual artists. Painters, sculptors, illustrators, all tried their hand at reimagining Melville’s great whaling epic through their works.
Antonella Rossini
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

La necesaria reforma de la Ley Foral de Turismo de Navarra a la luz de la Directiva de Servicios

open access: yesRevista Vasca de Administración Pública, 2016
This paper highlights the importance of the tourism sector to the Foral Community of Navarra and it sets out the need for an in depth reform of the actual regulation in order to adapt it to the Directive of Services, pointing several lines of action. The
Ignacio Ordoki Guarch
doaj   +1 more source

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