DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Identification of a transposon Tn3 sequence required for transposition immunity.
C H Lee, Arvind A. Bhagwat, Fred Heffron
openalex +2 more sources
Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition [PDF]
Jun Fu +9 more
openalex +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
This article discusses preliminary findings of a study on the transposition of the legal concept of genocide into 131 national jurisdictions. The specificities of this transposition into national criminal systems, as well as those related to the ...
Marie-Hélène GIRARD
doaj
Ovarian survival after pelvic radiation: transposition until the age of 35 years [PDF]
Ellen J. Hoekman +5 more
openalex +1 more source
Transposable element sequence fragments incorporated into coding and noncoding transcripts modulate the transcriptome of human pluripotent stem cells [PDF]
Isaac A. Babarinde +22 more
openalex +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Balloon dilatation of complete obstruction of the superior vena cava after Mustard operation for transposition of great arteries. [PDF]
Jassim Abdulhamed +3 more
openalex +1 more source

