Results 51 to 60 of about 145,661 (308)
What's new for us in strabismus?
Indian Journal of Ophthalmology, 2017 Strabismus is one of the most challenging subspecialties encountered in the field of ophthalmology. The concept of etiology of strabismus is being advanced with the development of newer imaging modalities and increased understanding of the genetics of ...
Pradeep Sharma +3 more
doaj +1 more source
Bulletin of the Institute of Mathematics Academia Sinica NEW SERIES, 2019 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
"Between Structure and Incident. A Sociological-Institutionalist Approach to the Riddle of Transposition Delays of European Food Safety Directives" [PDF]
, 2005 [From the Introduction]. The Dutch cannot expand their highway system as they like, because that gets them in conflict with European air quality standards; strictly enforcing the latter could also deal a death blow to the huge Dutch chicken industry ...
Ieva Gange +3 more
core
RNA interference is responsible for reduction of transgene expression after Sleeping Beauty transposase mediated somatic integration. [PDF]
, 2012 Integrating non-viral vectors based on transposable elements are widely used for genetically engineering mammalian cells in functional genomics and therapeutic gene transfer.
Anja Ehrhardt +7 more
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Lieux et espaces de la musique [PDF]
, 2018 L’article propose un retour réflexif sur le séminaire « Lieux et espaces de la musique » qui s’est tenu à l’EHESS de 2002 à 2014. Lancé par Patrice Veit et Michael Werner, auxquels se sont joints, par la suite, Denis Laborde, Karine Le Bail, Claire Guiu ...
Michael Werner, Werner, Michael
core +1 more source
De la complexité du métier d’ingénierie pédagogique en FLE [PDF]
Revue Roumaine d’Etudes Francophones, 2020 Language teaching is mainly a job of designing educational tools. The role of the professional teacher no longer consists only of teaching but also of designing teaching sequences adapted to the specific needs of his learners.
Mansour CHEMKHI
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source