Results 141 to 150 of about 12,761 (249)

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri   +26 more
wiley   +1 more source

Osteoarthritis: Epidemiology, Diagnosis, and Treatment

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru   +7 more
wiley   +1 more source

Current Landscape and Future Perspectives of Diabetic Retinopathy Therapy: Pharmacological Targets, Precision Laser Technology, and Clinical Evidence

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Targeted biological agents targeting VEGF, integrin, dopamine D2 receptor, ROCK, and BCL‐XL have entered the clinical trial phase and deserve particular attention. The treatment paradigm has shifted toward personalized and precision medicine, positioning optimized SML as a promising adjunctive therapy.
Xinying Hu   +7 more
wiley   +1 more source

Three different surgical approaches for transposition of the great arteries

open access: yesRevista Portuguesa de Cardiologia, 2013
Boban Thomas   +2 more
doaj   +1 more source

Atherosclerosis: Molecular Pathogenesis and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Molecular factors, like transforming growth factor beta (TGF‐β), mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase (PI3K), or cyclin‐dependent kinases (CDKs) 5 and 9, are essential modulators of atherosclerotic lesions. The novel, promising strategies for atherosclerosis treatment include therapies based on small interfering RNA (siRNA)
Jonatan Kaszubski   +3 more
wiley   +1 more source

Long-Term Results After Senning and Mustard Operations for d-Transposition of the Great Arteries: Atrial Switch Should Remain in Armamentarium. [PDF]

open access: yesEur J Cardiothorac Surg
Kari FA   +12 more
europepmc   +1 more source

Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 966-988, July 2026.
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo   +4 more
wiley   +1 more source

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