First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri +26 more
wiley +1 more source
Anaesthetic management of a paediatric patient with situs inversus totalis and congenitally corrected transposition of the great arteries undergoing adenotonsillectomy. [PDF]
Ozcan E.
europepmc +1 more source
Osteoarthritis: Epidemiology, Diagnosis, and Treatment
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru +7 more
wiley +1 more source
Is the Present Arterial Switch Operation Really a Perfect Surgical Option for the Patients With Transposition of the Great Arteries? [PDF]
Kim H.
europepmc +1 more source
Targeted biological agents targeting VEGF, integrin, dopamine D2 receptor, ROCK, and BCL‐XL have entered the clinical trial phase and deserve particular attention. The treatment paradigm has shifted toward personalized and precision medicine, positioning optimized SML as a promising adjunctive therapy.
Xinying Hu +7 more
wiley +1 more source
Three different surgical approaches for transposition of the great arteries
Boban Thomas +2 more
doaj +1 more source
Left ventricular assist device implantation and surgical repair in advanced congenitally corrected transposition of the great arteries. [PDF]
Xie W, Ge Y, Cao H.
europepmc +1 more source
Atherosclerosis: Molecular Pathogenesis and Therapeutic Interventions
Molecular factors, like transforming growth factor beta (TGF‐β), mitogen‐activated protein kinase (MAPK), phosphoinositide 3‐kinase (PI3K), or cyclin‐dependent kinases (CDKs) 5 and 9, are essential modulators of atherosclerotic lesions. The novel, promising strategies for atherosclerosis treatment include therapies based on small interfering RNA (siRNA)
Jonatan Kaszubski +3 more
wiley +1 more source
Long-Term Results After Senning and Mustard Operations for d-Transposition of the Great Arteries: Atrial Switch Should Remain in Armamentarium. [PDF]
Kari FA +12 more
europepmc +1 more source
Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo +4 more
wiley +1 more source

