Results 161 to 170 of about 12,761 (249)

Mending the Heart for Motherhood: Preconception Valve-in-Valve Replacement in Congenitally Corrected Transposition of the Great Arteries. [PDF]

CJC Pediatr Congenit Heart Dis
Bhat S, Thakkar R, Ellingson CJ, Singh J, Dehghani P.   +4 more
europepmc   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, Volume 269, Issue 3, Page 268-283, July 2026.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Transposition of the Great Arteries With Intact Ventricular Septum and Fetal-Onset Dilated Cardiomyopathy in a Neonate With a Homozygous NEXN Variant. [PDF]

Case Rep Pediatr
Geer D, Wakeling E, Goljan E, Robinson H, Swain J, Laurence C.   +5 more
europepmc   +1 more source

Placental Dysfunction and Congenital Heart Disease: Investigating the Placenta‐Heart Axis

Prenatal Diagnosis, Volume 46, Issue 8, Page 1193-1200, July 2026.
ABSTRACT Objective Concurrent development of the placenta and heart during early gestation suggests a shared biological basis for the co‐occurrence of abnormal placentation and congenital heart disease (CHD). This study investigated the association between placental vascular pathology and CHD type.
Natalie Lanners, Sarah U. Morton, Katherine Le, Steffy Blanco, Sara Mansoorshahi, Chrystalle Katte Carreon, Christina Ronai, Louise Wilkins‐Haug, Vidhya Annavajjhala, Jacqueline G. Parchem, Tina O. Findley   +10 more
wiley   +1 more source

Long-Term Outcome Following Prenatal Diagnosis of Transposition of the Great Arteries. [PDF]

Pediatr Cardiol
Lillitos P, Moriarty G, Witter T, Austin C, Miller O, Sharland GK, Simpson JM, Zidere V, Vigneswaran TV.   +8 more
europepmc   +1 more source

Right Ventricular Function Improves With Pulmonary Vasodilator Treatment in Pediatric Patients With Pulmonary Hypertension and Multivessel Pulmonary Vein Stenosis in a Single Center Cohort

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Pulmonary hypertension (PH) and right ventricular (RV) dysfunction increase mortality in multivessel pediatric pulmonary vein stenosis (PVS). Pulmonary vasodilator use is limited in PVS due to the perceived risk of pulmonary edema. We aimed to describe our experience with pulmonary vasodilators in PVS and to assess changes in RV function and ...
Catherine M. Avitabile, Kimberly Butler, Antara Mondal, David B. Frank, Yan Wang, Devon Ash, Laura Mercer‐Rosa, Michael L. O'Byrne, Ryan Callahan   +8 more
wiley   +1 more source

Long-Term Outcome After the En Bloc Rotation of the Outflow Tracts Including Patients With Congenitally Corrected Transposition of the Great Arteries. [PDF]

Eur J Cardiothorac Surg
Kreuzer M, Sames-Dolzer E, Tulzer A, Mair R, Gierlinger G, Seeber F, Bakos M, Mair R.   +7 more
europepmc   +1 more source

Iron Homeostasis at High Altitude in Patients With Pulmonary Hypertension

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Iron deficiency aggravates hypoxic pulmonary vasoconstriction, exacerbating the increase of pulmonary arterial pressure at high altitude (HA). This may be especially relevant for patients with pulmonary hypertension (PH) travelling to HA, who moreover have a high prevalence of iron deficiency. Currently, no data is available on iron parameters
Aurelia E. Reiser, Markus Thiersch, Max Gassmann, Simon R. Schneider, Laura Mayer, Stéphanie Saxer, Michael Furian, Richard Sparla, Esther I. Schwarz, Mona Lichtblau, Martina U. Muckenthaler, Silvia Ulrich   +11 more
wiley   +1 more source

A modification of the Nikaidoh procedure in double-switch operation for congenitally corrected transposition of the great arteries. [PDF]

JTCVS Tech
Ito T, Aoki M, Koshiyama H, Hagino I.
europepmc   +1 more source

Evidence for PDZ‐Binding Kinase in Lung Disease With an Emphasis on PAH

Pulmonary Circulation, Volume 16, Issue 3, July 2026.
ABSTRACT Originally named T‐cell‐originated Lymphokine‐activated killer protein kinase (TOPK), PDZ‐Binding Kinase (PBK) is a serine/threonine kinase that is a member of the family of mitogen‐activated protein kinases (MAPKKs), which is overexpressed in lung cancer and interstitial pulmonary fibrosis (IPF). Along these lines, recent work also shows that
Scott A. Barman, Zsuzsanna Bordan, David J. R. Fulton   +2 more
wiley   +1 more source