Results 191 to 200 of about 16,120 (219)

Hereditary transthyretin amyloidosis associated with a transthyretin variant Thr59Arg

Amyloid, 2017
Hereditary transthyretin (TTR) amyloidosis is characterized by ATTR amyloid deposits in various tissue sites and organs, such as peripheral nerves, heart, gastrointestinal tract, kidneys, eyes, and...
Tetsuya, Watanabe, Konen, Obayashi, Yohei, Misumi, Masayoshi, Tasaki, Satoru, Shinriki, Tomotaka, Ando, Takafumi, Akagami, Mitsuharu, Ueda, Taro, Yamashita, Shinichi, Hirotani, Yukio, Ando   +10 more
openaire   +2 more sources

Investigation into thiol conjugation of transthyretin in hereditary transthyretin amyloidosis

European Journal of Clinical Investigation, 1998
BackgroundFor all forms of amyloidosis, the amyloid‐generating mechanism is unknown. Familial amyloidotic polyneuropathy type I is caused by a variant transthyretin (TTR Met‐30). As electrospray ionization mass spectrometry (ESI‐MS) discloses both thiol‐conjugated and ‐unconjugated forms of wild‐type and variant TTR, we wanted to investigate the ...
O B, Suhr, Y, Ando, P I, Ohlsson, A, Olofsson, K, Andersson, E, Lundgren, M, Ando, G, Holmgren   +7 more
openaire   +2 more sources

Hereditary Transthyretin Amyloidosis Polyneuropathy

Seminars in Neurology
AbstractIn the last decade, we have witnessed dramatic improvements in the diagnosis, workup, management, and monitoring of patients with hereditary transthyretin amyloidosis (ATTRv). Updated imaging techniques (e.g., 99mTc-PYP scan) are increasingly being used in place of tissue biopsies for confirmation of disease.
Taha, Qarni, Orly, Moshe-Lilie, Michelle C, Kaku, Chafic, Karam   +3 more
openaire   +2 more sources

Liver transplantation and transthyretin amyloidosis

Muscle & Nerve, 2012
AbstractLiver transplantation as a specific treatment of transthyretin amyloidosis was first performed in 1990. The rationale for this treatment was that removal of the source (liver) of the amyloid precursor protein (mutated transthyretin) would stop progression of the disease. Indeed, after orthotopic liver transplantation (OLT), mutant transthyretin
openaire   +2 more sources

Isolated transthyretin valvular amyloidosis

European Heart Journal, 2023
Yi-Tsang Fu, Ling Kuo, Wen-Chung Yu
openaire   +2 more sources

Prevalence and clinical outcomes of transthyretin amyloidosis: a systematic review and meta‐analysis

European Journal of Heart Failure, 2022
Alexios S Antonopoulos, Ioannis Panagiotopoulos, Georgios Koutsis   +2 more
exaly  

Same same, but different? The neurological presentation of wildtype transthyretin (ATTRwt) amyloidosis

Amyloid: the International Journal of Experimental and Clinical Investigation: the Official Journal of the International Society of Amyloidosis, 2022
Felix Kleefeld, Carsten Tschope, Holger Amthauer   +2 more
exaly  

Characteristics of patients with autonomic dysfunction in the Transthyretin Amyloidosis Outcomes Survey (THAOS)

Amyloid: the International Journal of Experimental and Clinical Investigation: the Official Journal of the International Society of Amyloidosis, 2022
Angela Dispenzieri, Isabel Conceição, Marcia Waddington Cruz   +2 more
exaly  

Transthyretin amyloidosis

Amyloid, 1996
Merrill D. Benson, Tomoyuki Uemichi
openaire   +1 more source

A natural history analysis of asymptomatic TTR gene carriers as they develop symptomatic transthyretin amyloidosis in the Transthyretin Amyloidosis Outcomes Survey (THAOS)

Amyloid: the International Journal of Experimental and Clinical Investigation: the Official Journal of the International Society of Amyloidosis, 2022
TERESA Coelho, Isabel Conceição, Marcia Waddington Cruz   +2 more
exaly