Results 171 to 180 of about 5,567 (282)

Environment for the development of transversal competencies in school education

open access: yes, 2017
The contemporary socio-cultural and educational situation points the attention to the analysis and construction of opportunities for the formation and development of transversal competences in school education.
Tsankov, Nikolay
core  

Identifying core teamwork competencies for community-based health and social care professionals: an e-Delphi study. [PDF]

open access: yesBMC Med Educ
Aleo G   +8 more
europepmc   +1 more source

A MODEL FOR DEVELOPING TRANSVERSAL-METHODOLOGICAL COMPETENCIES IN FUTURE EDUCATORS

open access: yes
The modernization of higher education in Uzbekistan until 2030 aims to develop independent learning, critical thinking, and entrepreneurial skills. The competency-based approach enhances professional competence through innovative pedagogical technologies.
openaire   +2 more sources

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

open access: yesAdvanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng   +17 more
wiley   +1 more source

Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor

open access: yesAdvanced Science, EarlyView.
The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao   +11 more
wiley   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

open access: yesAdvanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang   +19 more
wiley   +1 more source

Enriched core competencies for health services and policy research-An update. [PDF]

open access: yesLearn Health Syst
McMahon M   +12 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy