Results 221 to 230 of about 1,364,085 (279)

From needs to design: teachers' perspectives on core components of culturally responsive SEL in Türkiye. [PDF]

Front Psychol
Alemdar M, Aşıkcan M.
europepmc   +1 more source

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source

Training in communication and teamwork skills in health sciences: A brief report of Spain. [PDF]

J Educ Health Promot
Bullón-Benito E, Alcalá-Cerrillo M, Poveda-García A, Ortiz-Piña M, Gonzalo-Ciria L, Álvarez-Martínez AJ.   +5 more
europepmc   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

Conceptual frameworks, competencies, contents and teaching methods in planetary health education for health students and professionals: a global systematic scoping review. [PDF]

BMC Med Educ
Carrion C, Llamas CA, Safitri ED, Domènech-Panicello C, Downward GS, Findyartini A, Greviana N, Murni IK, Lee SM, Llimós M, Moreno A, O'Brien SL, Ruiz-Mallén I, Soemantri D, Widyahening IS, Ranakusuma RW, Fitriani DY, O'Callaghan-Gordo C.   +17 more
europepmc   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Exploring the use of low-cost simulation in nursing education: a scoping review. [PDF]

BMJ Open
Frangi D, Bardacci Y, Magi CE, El Aoufy K, Longobucco Y, Iovino P, Amato C, Balestri C, Forciniti C, Rasero L, Iozzo P, Lucchini A, Bambi S.   +12 more
europepmc   +1 more source

Transversal Competences or How to Learn Differently

, 2016
openaire   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

AI Integration in Spanish Undergraduate Medical Education: National Cross-Sectional Study. [PDF]

JMIR Med Educ
Enériz Janeiro A, Pitombeira Pereira K, Mayol J, Crespo J, Carballo F, B Cabello J, Ramos-Casals M, Pérez Corbacho B, Turnes J.   +8 more
europepmc   +1 more source