Results 51 to 60 of about 5,329 (284)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Modified generalized Hadamard matrices and constructions for transversal designs

open access: yes, 2010
It is well known that there exists a transversal design TD_λ[k; u] admitting a class regular automorphism group U if and only if there exists a generalized Hadamard matrix GH(u, λ) over U.
128386   +4 more
core   +1 more source

Multifrequency Induced-Charge Electroosmosis

open access: yesMicromachines, 2019
We present herein a unique concept of multifrequency induced-charge electroosmosis (MICEO) actuated directly on driving electrode arrays, for highly-efficient simultaneous transport and convective mixing of fluidic samples in microscale ducts.
Kai Du   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Group divisible designs with block-size four [PDF]

open access: yes, 1977
It is proved that the obvious necessary conditions for the existence of a group divisible design with k = 4 are sufficient, except for the cases corresponding to the non-existing transversal designs T[4, 1; 2] and T[4, 1; 6]
Schrijver, A.   +7 more
core   +1 more source

Combinatorial aspects of covering arrays

open access: yesLe Matematiche, 2004
Covering arrays generalize orthogonal arrays by requiring that t -tuples be covered, but not requiring that the appearance of t -tuples be balanced.Their uses in screening experiments has found application in software testing, hardware testing, and a ...
Charles J. Colbourn
doaj  

Vitimação múltipla feminina ao longo da vida: uma revisão sistemática da literatura

open access: yesPsicologia & Sociedade, 2013
No contexto internacional assistimos a um crescente reconhecimento científico de que as mulheres, vítimas preferenciais de diferentes formas de vitimação, tendem a coo-experienciar outras formas de vitimação ao longo da vida.
Marlene Matos   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Linear spaces and transversal designs:k-anonymous combinatorial configurations for anonymous database search

open access: yes, 2012
Anonymous database search protocols allow users to query a database anonymously. This can be achieved by letting the users form a peer-to-peer community and post queries on behalf of each other.
Farràs, Oriol,, Stokes, Klara,
core   +1 more source

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