Results 81 to 90 of about 5,329 (284)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Resolvable Group Divisible Designs with Large Groups
, 2016 We prove that the necessary divisibility conditions are sufficient for the existence of resolvable group divisible designs with a fixed number of sufficiently large groups.
Lamken, Esther R. +2 more
core +1 more source
On Symmetric Transversal Designs STD8[24; 3]'s [PDF]
, 2010 The existence of a class regular symmetric transversal design STDλ[3λ;3] is equivalent to a generalized Hadamard matrix of order 3u over GF(3). Let nλ be the number of nonisomorphic STDλ[3λ;3]'s.
Teppei Hatono, Chihiro Suetake
core +1 more source
Revista Latino-Americana de Enfermagem, 2015 Objective:to identify and analyze the evidence available regarding evaluation of burden and quality of life of mothers who are caregivers for children and adolescents with chronic illnesses.Method:an integrative review, undertaken in the electronic ...
Eliza Cristina Macedo +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Group divisible designs with block-size four
, 2006 It is proved that the obvious necessary conditions for the existence of a group divisible design with k=4 are sufficient, except for the cases corresponding to the non-existing transversal designs T[4,1;2] and T[4,1;6]
Schrijver, A., Hanani, H., Brouwer, A.E.
core +1 more source
Designs from Local Random Quantum Circuits with SU(d) Symmetry
PRX QuantumThe generation of k-designs (pseudorandom distributions that emulate the Haar measure up to k moments) with local quantum circuit ensembles is a problem of fundamental importance in quantum information and physics.
Zimu Li +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source