Results 61 to 70 of about 115,769 (299)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
On the Transverse Strength of Ore Carriers
Journal of Zosen Kiokai, 1966 When a large ore carrier is floating in the full load condition, a large amount of ore load is acting on the double bottom downwards and a large amount of buoyancy is acting on the wing tank upwards. In this case, it is expected that the relative deflection between the side shell and the longitudinal bulkhead increases and induces large stresses in the
Mori, Masahiro +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
InformationReducing cement consumption in mortar systems is essential for lowering the environmental impact of cement-based materials. Conventional mix design approaches rely mainly on particle size distribution and fineness modulus, which do not fully capture the ...
Jorge Fernando Sosa Gallardo +4 more
doaj +1 more source
Shear transfer between precast prestressed bridge beams and in-situ concrete crosshead in continuous structures [PDF]
, 1988 A detailed investigation was made to study the shear transfer between precast prestressed beams and in-situ concrete in a relatively new method of construction of continuous bridge decks where the ends of precast beams are connected to an integral in ...
Mirtalaie, K, Mirtalaie, Kamal
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
On the Transverse Strength of A Torpedo Boat
Journal of Zosen Kiokai, 1966 Data of the transient transverse stresses during slamming obtained from sea tests showed that the transverse strength of a torpedo boat was considerably affected by the longitudinals, because the longitudinals were parts of strength members to resist the impact loads upon slamming another words, the external forces were transmitted to bottom ...
openaire +2 more sources
Transverse Strength of Ships [PDF]
, 1994 The research study presented in this thesis is principally concerned with the transverse strength problem of ship structures. The main interest of the study lies in naval ships such as frigates and small destroyers which usually have a rise of floor in ...
Tinik, Bulent
core
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source