Results 41 to 50 of about 564,916 (317)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
American sweetgum Liquidambar styraciflua (Altingiaceae) was first introduced to China over 60 years ago. It is an important tree species for increasing landscape value and promoting afforestation in urbanized areas of eastern China in the past 20 years.
You Li +4 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Cat Colony Caretakers' Perceptions of Support and Opposition to TNR
Trap, neuter and return (TNR) is a non-lethal approach to urban cat management used effectively internationally to decrease urban cat numbers, but deemed illegal in Australia.
Jacquie Rand +3 more
doaj +1 more source
House flies (Musca domestica L.) are common synanthropic pests associated with confined animal operations, including dairy farms. House flies can cause substantial nuisance and may transmit human and animal pathogens.
Levi K. Zahn, Alec C. Gerry
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
A mechanical insect trap [PDF]
In the course of some work at Rothamsted on the activity and abundance of insects, in which a light trap was used as a method of estimating the numbers of insects in a state of activity, it appeared advisable to have a further trapping method which did ...
Williams, C. B., Milne, P. S.
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Trabecular meshwork peeling technique of ab interno trabeculectomy – A retrospective review
Purpose: To assess 1-year outcomes of the trabecular meshwork peeling technique of ab interno trabeculectomy in patients with glaucoma. Methods: This retrospective study reviewed medical records of 117 eyes from 117 glaucoma patients who underwent ...
Ankush Mahajan +3 more
doaj +1 more source

